Results 141 to 150 of about 7,083,291 (346)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Effects of video-based natural restorative environments on mental health: a systematic review
BMC Public HealthBackground Mental health is an essential component of public health. However, many individuals today face serious mental health challenges. Video-based Natural Restorative Environments (VNREs) have shown promising potential in the field of mental health.
Dan Rong Han, Kamal Sabran
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
New Media Spaces and New Media Objects
, 2009 The paper deals with three artistic examples of humanistic transposition of smart technologies that reshape our reality. Computer vision technology redefines the classical notions of space that we enhabit and repostulates Shakespear's verse “All the world is a stage.” New media objects that simultaneously participate in our everyday life and in the ...
openaire +1 more source
A New Big Data Architecture for Analysis: The Challenges on Social Media [PDF]
, 2023 Abdessamad Essaidi, Mostafa Bellafkih
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Neoliberal Media Making the Public Interest and Public Choice Theory Obsolete: Need for a New Theory [PDF]
, 2019 Vasupradha Srikrishna
openalex +1 more source