Results 71 to 80 of about 6,314,191 (290)

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1222-1235, May 2025.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

New Media & Intermedia Visiting Artist Speaker Program, Fall 2009 [PDF]

open access: yes, 2009
The New Media Department and the Intermedia MFA Program are requesting funds to help support a fall lecture series. All of the visiting artists proposed in our Fall lecture series will publicly share their expertise in the following areas: an evening ...
University of Maine- New Media Department
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Ole Miss Agency Wins $2,000 Award in AT&T Challenge [PDF]

open access: yes, 2014
Competition provides real-world experience for integrated marketing communications ...
School of Journalism and New Media
core   +1 more source

Tobacco control challenges in China: Big data analysis of online tobacco marketing information

open access: yesInternational Journal of Nursing Sciences, 2020
Objective: To develop tobacco control strategies by analyzing online tobacco marketing information in China. Methods: Using web-crawler software, this study acquired 106,485 pieces of online tobacco marketing information published on 11 different ...
Xiuli Wang, Ying Xiong, Wenwen Zhao
doaj  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Top-N-Targets-Balanced Recommendation Based on Attentional Sequence-to-Sequence Learning

open access: yesIEEE Access, 2019
User's behaviors and preferences alter with the temporal evolution dynamically, which leads to low performance, such as the Hit Rate and Normalized Discounted Cumulative Gain (NDCG).
Xingkai Wang   +3 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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