Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Effects of New Media-Based Education on the Treatment of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. [PDF]
J Med Internet ResFan W, Tao Y, Shi J, Ye F.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Retracted: The Construction of Civics in University English Courses in the New Media Environment. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
New media, lifestyle transformation, and public health: unraveling the digital divide in China. [PDF]
Front Public HealthMa R, Zheng T, Wang M, Gu J.
europepmc +1 more source
Retracted: An Analysis of the Cultivation Methods of Visual Communication Design in New Media Environment. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Correction: New media, lifestyle transformation, and public health: unraveling the digital divide in China. [PDF]
Front Public HealthMa R, Zheng T, Wang M, Gu J.
europepmc +1 more source
Retracted: The Skill Training of Reading Music in the Teaching of Solfeggio and Ear Training in the New Media Environment. [PDF]
Appl Bionics Biomech, 2023 And Biomechanics AB.
europepmc +1 more source