Results 101 to 110 of about 3,009,168 (307)

Playing to win or trying your best: Media representations of national anxieties over the role of sport participation during the 2002 commonwealth games. [PDF]

, 2004
In the last few years, growing concern has emerged in New Zealand sport about the shift towards a more commercial or professionalised model of sport and away from a mass participation-based model. In the midst of a relatively intense period of debate and
Bruce, Toni, Pope, Clive C., Wensing, Emma H.   +2 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

How have MOOCs been portrayed in the New Zealand public media?

Journal of Open, Flexible and Distance Learning, 2020
Reports of Massive Open Online Courses (MOOCs) hit the news media from 2012 with messages of disruption to existing higher education systems.  However, several years on their role is still evolving.
Yvonne Rowan, Maggie Hartnett
doaj   +2 more sources

Rethinking professional learning in higher education: a study on how the use of Open Educational Resources triggers the adoption of Open Educational Practice [PDF]

, 2017
This study explores how the practices of higher education educators evolve towards open educational practice (OEP) as they use open educational resources (OER) as a form of social media.
Hood, Nina, Kaatrakoski, Heli, Littlejohn, Allison   +2 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Social Communication between Traditional and the New Mass-Media

EIRP Proceedings, 2014
The means of communication, from the most simple and natural ones – such as gestures and voice, to the most complex and developed ones – such as the new electronic media, have constantly brought changes to the society, their own transformation being ...
Andreea-Maria Tîrziu, Cătălin I. Vrabie   +1 more
doaj  

Editorial: BILETA special issue: Technology and Legal Education [PDF]

, 2014
Fragmentation and convergence are two discoursal lenses that have been used to view changes that have taken place in the domains of legal services,the legal profession, regulation and legal education. While they may appear orthogon al, the relationships
Maharg, P
core   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

New Media – New Educative Challenges for Catechesis

Roczniki Teologiczne, 2018
The development of the Internet and modern communication tools is the subject of research of various scientific disciplines. For many years, polish researchers have been conducting both quantitative and qualitative studies on the degree of Internet use and the impact of new technologies and their tools on the contemporary young generation. The Catholic
openaire   +1 more source