Results 41 to 50 of about 3,009,168 (307)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Artificial intelligence in media education: potential, challenges and prospects

open access: yesEdukacyjna Analiza Transakcyjna
This article discusses the role of artificial intelligence (AI) in media education, highlighting its potential for developing students' media literacy, the challenges associated with its implementation, its threats, and future directions for development.
Katarzyna Adamczyk
doaj   +1 more source

Virtual reality in theatre education and design practice - new developments and applications [PDF]

open access: yes, 2009
The global use of Information and Communication Technologies (ICTs) has already established new approaches to theatre education and research, shifting traditional methods of knowledge delivery towards a more visually enhanced experience, which is ...
Beardon C.   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Towards a situated media practice: Reflections on the implementation of project-led problem-based learning [PDF]

open access: yes, 2013
In the field of media practice education, project-based learning is utilized as a major pedagogic paradigm with the aim of mirroring professional practice within the curriculum.
Hanney, Roy
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An Analysis of the Utilisation of Audiovisual Archives in Higher Humanities and Arts Education

open access: yesTeorie vědy, 2010
Audiovisual archives with an advanced communication infrastructure are a rapidly developing tool whose unique potential in the realm of education has not been sufficiently explored yet.
Michal Klodner, Lucia Udvardyová
doaj  

New communication media challenges for supervisors and external doctoral students [PDF]

open access: yes, 2011
This study investigated perceptions of doctoral students and supervisors in an Australian university about communication challenges in doctoral distance education, frequency of communication between candidate and supervisors, satisfaction with meetings ...
Albion, Peter R., Erwee, Ronel
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Using social media to support teaching and learning in higher education: an analysis of personal narratives

open access: yesResearch in Learning Technology, 2020
The increasing trend of using new media technologies and particularly social media (SM) among students provides an advantage for lecturers. Apparently their importance accelerated with the application of social distancing during a pandemic crisis such as
Nurten Kara   +2 more
doaj   +1 more source

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