Results 31 to 40 of about 468,644 (218)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Artificial intelligence in media education: potential, challenges and prospects

Edukacyjna Analiza Transakcyjna
This article discusses the role of artificial intelligence (AI) in media education, highlighting its potential for developing students' media literacy, the challenges associated with its implementation, its threats, and future directions for development.
Katarzyna Adamczyk
doaj   +1 more source

The impact of media and information literacy on students’ acquisition of the skills needed to detect fake news

Journal of Media Literacy Education, 2022
This research investigated the impact of media and information literacy (MIL) on education faculty students’ acquisition of the skills needed to detect fake news.
Reem M Al Zou'bi
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

An Analysis of the Utilisation of Audiovisual Archives in Higher Humanities and Arts Education

Teorie vědy, 2010
Audiovisual archives with an advanced communication infrastructure are a rapidly developing tool whose unique potential in the realm of education has not been sufficiently explored yet.
Michal Klodner, Lucia Udvardyová
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Digital media literacy and perceived fake news handling skills among Arab social media users: evidence from a cross-national survey

Frontiers in Communication
IntroductionThis study examines the relationship between digital media literacy and supporting the ability of Arab social media users to confront fake news and misinformation spread through these networks, particularly in light of the rapid ...
Hossam Fayez, Mohammad Ali Alquaary, Nawal Abdullah Al-Hazwarh, Abdulbaset Mohammed Alhattami, Mahdi Mohammed Haidar Saleh   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TOWARDS UTILIZING NEW DIGITAL MEDIA TECHNOLOGIES FOR THE PROMOTION OF PEACE EDUCATION IN NIGERIA

African Journal of Teacher Education, 2012
Recent events in Nigeria have shown that the country cannot move forward without considering peace education in primary, secondary and tertiary institutions.
James Okolie-Osemene
doaj   +1 more source