Results 91 to 100 of about 1,301,382 (246)

The role of alliance management, big data analytics and information visibility on new-product development capability. [PDF]

Ann Oper Res, 2021
Dubey R, Bryde DJ, Graham G, Foropon C, Kumari S, Gupta O.   +5 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Product Creativity as an Identity Issue: Through the Eyes of New Product Development Team Members. [PDF]

Front Psychol, 2021
Park JS, Suzuki S.
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Pharmacokinetic bioequivalence of the fixed-dose combination of pertuzumab and trastuzumab administered subcutaneously using a handheld syringe or an on-body delivery system

Journal of Cancer Research and Clinical Oncology
Purpose This randomized, open-label, two-arm, parallel-group, single dose, multi-center phase I study (ClinicalTrials.gov ID, NCT05275010) investigated the comparability of the pharmacokinetics of a new formulation combining pertuzumab (P) and ...
Chris Wynne, Bei Wang, Rong Deng, Junyi Li, Daniel Eiger, Fabiola Bene Tchaleu, Sarah Heeson, Eleonora Restuccia   +7 more
doaj   +1 more source

Correction: Unpacking the importance of intangible skills in new product development and sustainable business performance; strategies for marketing managers. [PDF]

PLoS One, 2021
Ali S, Li G, Yang P, Hussain K, Latif Y.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Novel PBM for Nanomilling of Drugs in a Recirculating Wet Stirred Media Mill: Impacts of Batch Size, Flow Rate, and Back-Mixing

Pharmaceutics
We examined the evolution of fenofibrate (FNB, drug) particle size distribution (PSD) during the production of nanosuspensions via wet stirred media milling (WSMM) with a cell-based population balance model (PBM).
Hamidreza Heidari, Nontawat Muanpaopong, Gulenay Guner, Helen F. Yao, Donald J. Clancy, Ecevit Bilgili   +5 more
doaj   +1 more source

Impact of knowledge management capabilities on new product development performance through mediating role of organizational agility and moderating role of business model innovation. [PDF]

Front Psychol, 2022
Idrees H, Hynek J, Xu J, Akbar A, Jabeen S.   +4 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source