Results 81 to 90 of about 1,301,382 (246)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Knowledge-sharing hostility, knowledge manipulation, and new product development performance. [PDF]

Front Psychol, 2022
Cai R, Ma Y.
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Rational design of polymeric dielectrics guided by insightful understanding of electron transfer/transport in aperiodic systems

npj Computational Materials
Electron transfer and transport constitute the fundamental mechanisms governing the performance of polymeric dielectrics, yet their microscopic nature remains elusive due to the intrinsic complexity of aperiodic condensed states.
Shixun Hu, Li Meng, Mingti Wang, Jiahui Zhang, Jun Hu, Hao Yuan, Qi Li, Jinliang He   +7 more
doaj   +1 more source

Nutritional priorities, practices and preferences of athletes and active individuals in the context of new product development in the sports nutrition sector. [PDF]

Front Sports Act Living, 2023
Carey CC, Doyle L, Lucey A.
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An investigation of most important internal and external organizational factors effect on new product performance in food industries

تحقیقات بازار یابی نوین, 2014
New products are critical and undeniable factors for companies that operate in a competitive and changing environment. Many researchers have sought to identify factors that affect the success of new product. This research seeks to identify and categorize
Hamid raza Rezvani, Akram sadat Rashidaei   +1 more
doaj  

Sensory Analysis and Consumer Research in New Product Development. [PDF]

Foods, 2021
Ruiz-Capillas C, Herrero AM.
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source