Results 81 to 90 of about 1,302,412 (246)
The role of alliance management, big data analytics and information visibility on new-product development capability. [PDF]
Ann Oper Res, 2021 Dubey R +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Product Creativity as an Identity Issue: Through the Eyes of New Product Development Team Members. [PDF]
Front Psychol, 2021 Park JS, Suzuki S.
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Correction: Unpacking the importance of intangible skills in new product development and sustainable business performance; strategies for marketing managers. [PDF]
PLoS One, 2021 Ali S, Li G, Yang P, Hussain K, Latif Y.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Cancer Research and Clinical OncologyPurpose This randomized, open-label, two-arm, parallel-group, single dose, multi-center phase I study (ClinicalTrials.gov ID, NCT05275010) investigated the comparability of the pharmacokinetics of a new formulation combining pertuzumab (P) and ...
Chris Wynne +7 more
doaj +1 more source
Impact of knowledge management capabilities on new product development performance through mediating role of organizational agility and moderating role of business model innovation. [PDF]
Front Psychol, 2022 Idrees H +4 more
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
PharmaceuticsWe examined the evolution of fenofibrate (FNB, drug) particle size distribution (PSD) during the production of nanosuspensions via wet stirred media milling (WSMM) with a cell-based population balance model (PBM).
Hamidreza Heidari +5 more
doaj +1 more source