Results 41 to 50 of about 5,290,284 (268)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk +9 more
wiley +1 more source
The Determinants of New Product Performance in Malaysian Industry
Journal of ASEAN Studies, 2014 The literature on new product development is growing but Malaysia manufacturing industry often lacks these discussions. Therefore, this paper focuses on linking the determinants of an effective product development process and new product performance ...
Oon Fok-Yew
doaj +1 more source
Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig +13 more
wiley +1 more source
Design for manufacture and sustainability in new product development [PDF]
, 2010 Design for manufacture is well recognised by industry and is about optimising design to aid production. Today there is a significant and growing trend of recognising what happens to a product once its user phase has finished.
De Coster, R +3 more
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
mAbs, 2020 Disulfide bond reduction, which commonly occurs during monoclonal antibody (mAb) manufacturing processes, can result in a drug substance with high levels of low molecular weight (LMW) species that may fail release specifications because the drug’s safety
Zhijun Tan +14 more
doaj +1 more source
An empirical investigation into the use of product development in the educational furniture industry : a thesis presented in fulfilment of the requirements for the Master of Technology in Product Development at Massey University, Palmerston North, New Zealand [PDF]
, 2001 An empirical investigation into the use of product development in the educational furniture industry is summarised in this thesis. New Zealand furniture manufacturers are facing increased competition from imported furniture and are also exporting more ...
Morgan, Jeffrey Martin
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
PharmaceuticalsBackground: Renal fibrosis is a common pathological feature of all progressive chronic kidney disease (CKD). Eucommiae cortex (EC) is a valuable economic tree species endemic to China.
Zhengyou He +9 more
doaj +1 more source
Metabolites, 2022 Ganoderma lucidum P. karst is an edible fungus that is used in traditional medicine and contains triterpenoids as the major phytoconstituents. Ganoderic acids are the most abundant triterpenoids that showed pharmacological activity.
Mohd Hafizur Rehman Ansari +4 more
doaj +1 more source