Results 41 to 50 of about 5,305,995 (318)
Reengineering Biomedical Engineering Curricula: A New Product Development Approach [PDF]
, 2002 Product development engineers in medical industries have created design control procedures to ensure high quality designs that are as error-free as possible.
Ropella, Kristina M. +2 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Design for manufacture and sustainability in new product development [PDF]
, 2010 Design for manufacture is well recognised by industry and is about optimising design to aid production. Today there is a significant and growing trend of recognising what happens to a product once its user phase has finished.
De Coster, R +3 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
mAbs, 2020 Disulfide bond reduction, which commonly occurs during monoclonal antibody (mAb) manufacturing processes, can result in a drug substance with high levels of low molecular weight (LMW) species that may fail release specifications because the drug’s safety
Zhijun Tan +14 more
doaj +1 more source
An empirical investigation into the use of product development in the educational furniture industry : a thesis presented in fulfilment of the requirements for the Master of Technology in Product Development at Massey University, Palmerston North, New Zealand [PDF]
, 2001 An empirical investigation into the use of product development in the educational furniture industry is summarised in this thesis. New Zealand furniture manufacturers are facing increased competition from imported furniture and are also exporting more ...
Morgan, Jeffrey Martin
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
PharmaceuticalsBackground: Renal fibrosis is a common pathological feature of all progressive chronic kidney disease (CKD). Eucommiae cortex (EC) is a valuable economic tree species endemic to China.
Zhengyou He +9 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Mainstay chemotherapy for malaria is often faced with the problem of instability and poor bio-distribution thus resulting in impaired pharmacokinetics. Nanomedicine has been acclaimed for its success in drug delivery and improved efficacy. The aim of the
Oyetunde Oyeyemi +7 more
doaj +1 more source
mAbs, 2020 Disulfide bonds play a crucial role in folding and structural stabilization of monoclonal antibodies (mAbs). Disulfide bond reduction may happen during the mAb manufacturing process, resulting in low molecular weight species and possible failure to meet ...
Peifeng Tang +11 more
doaj +1 more source