Results 61 to 70 of about 5,290,284 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Green Technologies and SustainabilityThe automotive industry currently relies heavily on internal combustion engine (ICE) technology, which consumes large amounts of fossil fuels and significantly contributes to global environmental degradation and the ongoing energy crisis.
Vijay Bhooshan Kumar +3 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2017 In the pharmaceutical industry, the analysis of atropisomers is of considerable interest from a scientific and regulatory perspective. The compound of interest contains two stereogenic axes due to the hindered rotation around the single bonds connecting ...
Ling Zhang +4 more
doaj +1 more source
Robust Stabilization of a Class of Nonlinear Systems via Aperiodic Sensing and Actuation
IEEE Access, 2020 This article proposes a framework to design a robust controller for a class of nonlinear networked control systems using aperiodic feedback information.
Niladri Sekhar Tripathy +3 more
doaj +1 more source
Modified Stage-Gate: A Conceptual Model of Virtual Product Development Process [PDF]
, 2009 In today’s dynamic marketplace, manufacturing companies are under strong pressure to introduce new products for long-term survival with their competitors.
Ahmed, Shamsuddin +2 more
core +4 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Real-time new product development in financial services: Some managerial implications [PDF]
, 1998 A review of the various models of New Product Development (NPD) process shows that although different approaches have been proposed, they are in fact all variants on a linear theme: some may include feedback loops, but they all essentially advocate that ...
Blackman, ID, Dengler, S, Naude, P
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Trust in ICT-Based New Product Development - Guidelines for Virtual New Product Development Teams [PDF]
The traditional process of new product development is focusing on an intra-organizational workflow, which should - in its ideal form - be done by virtual interdisciplinary teams.
Haas, Rainer +2 more
core +1 more source
A novel approach to collaborative product development in the medical-equipment industry [PDF]
, 2013 In this study, we summarise the requirements for collaborative product development based on our investigation of the differences in the resources and tools that are needed for the various stages of collaborative product development and the needs of ...
Chien-Lung, Hsu, Tseng, Kevin C
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