Results 81 to 90 of about 23,260,635 (261)

Measuring consumption growth: the impact of new and better products [PDF]

open access: yes
This study describes how the U.S. government measures real consumption growth and how it tries to take account of a complicating factor: that the goods and services offered to consumers change over time; new products are introduced and old products are ...
Peter J. Klenow
core  

Empathic Products - D2.3: Guidelines for the Design of Empathic Products

open access: yes, 2015
This document presents a synthesis of lessons learnt during the Empathic Products project in the form of guidelines for the design of empathic ...
Parviainen, Päivi   +3 more
core   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Guide to Reporting and Initial Investigation of Quality Defects in Medicinal Products for Human and Veterinary Use

open access: yes, 2021
This is an industry guide for the following stakeholder groups: - marketing authorisation holders (MAHs) - registration holders - clinical trial sponsors - manufacturers - wholesalers This guide covers the reporting to the Health Products ...
Health Products Regulatory Authority (HPRA)
core  

Development and shelf life stability of new products for Pacific saury (Cololabis saira). [PDF]

open access: yesJ Food Sci Technol, 2023
Huang CC   +9 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

New Zealand and the Protocol to Eliminate Illicit Trade in Tobacco Products: consultation document

open access: yes, 2015
This consultation paper explores what legislative reforms, and other changes, would be needed if New Zealand were to become a party to the Protocol to Eliminate Illicit Trade in Tobacco Products.
Ministry of Health (New Zealand)
core  

Host-defence-related proteins in cows’ milk

open access: yesAnimal, 2012
Milk is a source of bioactive molecules with wide-ranging functions. Among these, the immune properties have been the best characterised. In recent years, it has become apparent that besides the immunoglobulins, milk also contains a range of minor immune-
T.T. Wheeler   +7 more
doaj   +1 more source

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