Results 81 to 90 of about 67,776 (202)

In Vitro Metabolism of a Benzofuran-Substituted Nitazene: Ethyleneoxynitazene

open access: yesMetabolites
Background/Objectives: New synthetic opioids (NSOs) like nitazenes pose significant public health risks due to their high potency and increasing prevalence. Ethyleneoxynitazene, a benzofuran-containing nitazene, recently emerged on the illicit market and
Omayema Taoussi   +8 more
doaj   +1 more source

Research Progress on Detection of New Psychoactive Substance Piperazines in vivo

open access: yesFayixue Zazhi
Piperazines are a class of new psychoactive substances with hallucinogenic effects that affect the central nervous system by affecting the level of monoamine neurotransmitters.
LIU Jin-ting   +6 more
doaj   +1 more source

New Psychoactive Substances: towards a conceptual delimitation

open access: yesAnálise Social, 2019
New Psychoactive Substances (NPS) are a relatively recent phenomenon characterized by continuous expansion throughout more or less the entire world in the last decade. They include a diversity of natural or synthetic substances that are not yet on official lists and whose great variety and rapid transformations make the NPS concept itself hard to ...
Susana Henriques   +2 more
openaire   +5 more sources

The impact of lifetime substance use on psychiatric comorbidities and treatment seeking in patients with alcohol use disorders

open access: yesScientific Reports
It is well-recognized that individuals with alcohol-related disorders often use other psychoactive substances; however, systematic research on this topic remains limited.
Piotr Engelgardt   +4 more
doaj   +1 more source

Regional Variation in Attitude of Mental Health Professionals Towards Tackling Illicit Drug-use and Drug-related Disorders [PDF]

open access: yes, 2017
This study sought to assess the attitudes of Mental Health Professionals (MHPs) towards tackling illicit drug use and drug-related disorders in Nigeria and to explore regional variations in attitude. Based on the validated Substance Abuse Attitude Survey
Akinola, O. (Olubusayo)   +3 more
core  

Clinical characteristics in new psychoactive substance users: A single center study. [PDF]

open access: yesMedicine (Baltimore), 2023
Su YJ   +4 more
europepmc   +1 more source

Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Identifying possible new biological activities of psychoactive substances belonging to various chemical classes may lead to a better understanding of their mode of action and side effects. We report here that amines structurally related to amphetamine, a
Andrea Angeli   +4 more
doaj   +1 more source

Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]

open access: yes, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Neuropharmacological characterization of the new psychoactive substance methoxetamine

open access: yesNeuropharmacology, 2017
The use of new psychoactive substances (NPS) is steadily increasing. One commonly used NPS is methoxetamine (MXE), a ketamine analogue. Several adverse effects have been reported following MXE exposure, while only limited data are available on its neuropharmacological modes of action. We investigated the effects of MXE and ketamine on several endpoints
Hondebrink, Laura   +5 more
openaire   +4 more sources

Hexahydrocannabinol Pharmacology, Toxicology, and Analysis: The First Evidence for a Recent New Psychoactive Substance. [PDF]

open access: yesCurr Neuropharmacol, 2023
Graziano S   +5 more
europepmc   +1 more source

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