Results 61 to 70 of about 4,873,053 (351)

Health Care Reforms, Power Concentration, and Receding Citizen Participation

open access: yesRisk Management and Healthcare Policy, 2023
Daniel Simonet Department of Management, Strategy & Entrepreneurship, American University of Sharjah, Sharjah, United Arab EmiratesCorrespondence: Daniel Simonet, Email dsimonet@aus.eduAbstract: The article highlights several outstanding features of ...
Simonet D
doaj  

Ineficiência, fragilização e duplicidade. o velho estado novo perante a emigração para frança (1960-1968)

open access: yesLer História, 2009
Between 1960 and 1968, the Portuguese government managed modernization, economic growth and trade openness to Europe in an ambiguous way. This processes that profoundly transformed the society have not been politically accepted.
Victor Pereira
doaj   +1 more source

"They see me as mentally ill": the stigmatization experiences of Chinese menopausal women in the family

open access: yesBMC Women's Health, 2023
Background Menopausal women are regarded as “abnormal people” in China and are often discriminated against and ostracized, especially in the privacy of their homes. However, research on the stigmatization of menopausal women in China is limited.
Qiong Li   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

STRATEGY AS DISCURSIVE PRACTICE IN A BRAZILIAN PUBLIC UNIVERSITY: A LOOK UNDER THE PERSPECTIVE OF CRITICAL DISCOURSE ANALYSIS [PDF]

open access: yes, 2014
The aim this article a critical discursive analysis of the “management plan” genre of a public institution of higher education, from 2012 to 2015, located in southeast Brazil.
Baêta, Odemir Vieira   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Training and Retaining Public Servants for the Future

open access: yesTransylvanian Review of Administrative Sciences
Demographic changes with an ageing popula­tion and declining birth rates, alongside economic challenges, have implications for the public service labour market.
Karen Johnston, Andrew Massey
doaj   +1 more source

The Impact of Strategic Planning on the Reform of Lebanese Public Administration [PDF]

open access: yesRevista de Management Comparat International, 2019
For Lebanon to reach its future obligations prior to the implementation of “Capital Investment Plan” or what we called “Cedar Project”, the need for strategy in Lebanese Public Administration reform is substantial. An efficient and effective mechanism to
Charbel El AMMAR
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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