Results 51 to 60 of about 28,966,456 (308)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Smart City Research: Contextual Conditions, Governance Models, and Public Value Assessment [PDF]

, 2016
There are three issues that are crucial to advancing our academic understanding of smart cities: (1) contextual conditions, (2) governance models, and (3) the assessment of public value.
Meijer, Albert J., Public Management, UU LEG Research USG Public Matters, Bolívar, Manuel Pedro Rodríguez, UU LEG Research USG Public Matters Public Governance and Management, Gil-Garcia, J. Ramon   +5 more
core   +1 more source

Training and Retaining Public Servants for the Future

Transylvanian Review of Administrative Sciences
Demographic changes with an ageing popula­tion and declining birth rates, alongside economic challenges, have implications for the public service labour market.
Karen Johnston, Andrew Massey
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Gestão Pública: entre a visão clássica da Administração Pública e o novo paradigma da Governação Pública

Revista Enfoques, 2009
This text aims at accounting for the evolution of the reform movement that goes from Public Administration to Governance, while going through New Public Management.A movement that to be understood requires, more than a sequence of steps, the ...
André Azevedo Alves, José Manuel Moreira   +1 more
doaj  

Understanding co-production as a new public governance tool

Policy & Society, 2018
Co-production has become a buzzword for both scholars and practitioners in the past decade. This introduction to the thematic issue ‘Co-production: Implementation problems, new technologies and new designs’ unpacks the concept of co-production and ...
Maddalena Sorrentino, Mariafrancesca Sicilia, Michael Howlett   +2 more
doaj   +1 more source

Efficient Financial Management of Local Government Units: Postulates of Economic Doctrine and Instruments

Problemy Zarządzania, 2017
New conditions and challenges emerging in front of the public sector require the public finances management system to be reorganized. It also applies to the finances of local government units. The authors of the elaboration, while seeking to answer the
Marzanna Poniatowicz, Ryta Dziemianowicz
doaj   +1 more source

Paradigms of Public Administration: From Traditional Public Administration to Good Governance [PDF]

مدیریت دولتی, 2012
Since the evolution of Public administration as an academic and scientific discipline, different competitive approaches have come forward in this area.
Habibollah Salarzehi, Habib Ebrahimpour
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source