Results 61 to 70 of about 28,966,456 (308)

The Movement beyond the new public management: public governance practices in Italian public organisations

open access: yes, 2013
Purpose – The chapter aims to analyse specific management tools which can be used to facilitate public governance practices, such as the process of stakeholder involvement.Methodology/approach – By means of both a theoretical discussion and an empirical ...
Luca Gnan   +11 more
core   +2 more sources

Transformation of Public Administration in the Context of Contingent Social Systems

open access: yesRUDN Journal of Political Science
This study examines the transformation of public administration theory and practice in the new context of contingent social systems. The relationship between the bifurcation development of modern society and trends in administrative reforms is determined.
Leonid V. Smorgunov
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Improving New Zealand water governance: challenges and recommendations [PDF]

open access: yes, 2014
The overwhelming majority of New Zealand’s exports – not least agricultural and horticultural – require water, and in large quantities. Indeed, in many respects water is New Zealand’s largest export.
Elizabeth Eppel, Eppel, Elizabeth
core   +1 more source

Audyt wewnętrzny jako mechanizm ładu organizacyjnego w szkolnictwie wyższym

open access: yesStudia i Materiały
Purpose: The primary objective of the study is to verify the use of the internal audit function as an instrument of New Public Management (NPM) and a mechanism for improving the activities of Polish universities. Design/Methodology/Approach: The study
Grzegorz Palus
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Positioning Accountability in European Governance: an Introduction [PDF]

open access: yes, 2010
The special issue of which this paper forms the introduction takes as its central focus one particular aspect of democratic governance: accountability.
Mair, P.   +4 more
core  

Public and Nonprofit Management and the “New Governance” [PDF]

open access: yesThe American Review of Public Administration, 2008
Many public functions originally performed primarily by state actors now routinely rest not with the responsible government agencies but with a host of nongovernmental, third-party surrogates or proxies. There has also been an increase in partnerships and collaboration between nonprofits, corporations, and governments, necessitating new skills and ...
Leda McIntyre Hall, Sheila Suess Kennedy
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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