Results 51 to 60 of about 5,161,561 (243)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

volume 74, no. 12, December 1974 [PDF]

open access: yes, 1974
Alumni Fund John P. Hannon Named Acting Vice President for Public Affairs Bryant College President’s Club 1973-74 Idea of Women’s Equity News from the Campus News of Some Special People Promotions and Appointments Center for Management Development Class ...

core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

New Zealand freshwater management and agricultural impacts [PDF]

open access: yes
In New Zealand, it is increasingly recognised, including by government, that water resource allocation and water quality are issues of national importance.
Cullen, Ross   +2 more
core   +1 more source

Public Administration Trends and Approaches: New Public Management [PDF]

open access: yes, 2016
Result Oriented Management (ROM) is a contemporary management philosophy and approach which focuses on the appropriate and timely achievement of relevant goal and objectives through strategic planning, systematic implementation and resource utilization,
Dikhaminjia, I., Miminoshvili, M.
core  

New development : value for money (VFM) in public services - the importance of organisational culture [PDF]

open access: yes, 2016
VFM has been a key aspect of public service management for several decades and its importance has been raised in recent years as a consequence of austerity.
Barrow, Lynne   +2 more
core   +3 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

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