Results 41 to 50 of about 6,267 (258)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Eisenhower administration and revolutionary justice in Cuba: “Humanitarian” considerations?
Études Caribéennes, 2023 While the Eisenhower administration had observed the utmost discretion regarding the atrocities committed by the dictatorship of Fulgencio Batista in Cuba, it instead voiced its criticism when the new power led by President Manuel Urrutia decided to ...
Salim Lamrani
doaj +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
THE NEW SINCERITY IN AMERICAN LITERATURE
, 2020 The New Sincerity is a provocative mode of literary interpretation that focuses intensely on coherent connections that texts can build with readers who are primed to seek out narratives and literary works that rest on clear and stable relationships between dialectics of interior/exterior, self/others, and meaning/expression.
openaire +2 more sources
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Metacritic Journal for Comparative Studies and TheoryIn this paper I take two recent cases of literary self-portraits to argue that both function as artistic manifestations of the 1990’s concept of New Sincerity, which was proposed by David Foster Wallace in “E Unibus Pluram” (1993), and theorized by Adam ...
Santiago Gutiérrez Echeverría
doaj +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Вестник Волгоградского государственного университета: Серия 2. ЯзыкознаниеThe relevance of the study is determined by the demand for “new sincerity” that has emerged in society. Reflecting modern trends, mass media highlight the urgency of research into this phenomenon from various angles.
Ekaterina A. Zvereva +2 more
doaj +1 more source