Results 31 to 40 of about 19,404,997 (303)
Tradition and Political Economy in the Viceroyalty of New Spain (18th century)
Ибероамериканские тетрадиThe legal traditions of the Spanish Empire, which had certain particularities but were always in line with the imperial Catholic culture, played a major role in the development and expansion of the Hispanic world in the Ancien Régime.
J. R. Bravo
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Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Evolution of freedom of information related law in Spain: new prospects for a more open government [PDF]
, 2006 The evolution of FOI law in Spain over the last 30 years is analysed. The process starts with the Constitution of 1978 and goes on with a series of FOI related laws on the management of public administration services, the automatic processing of personal
Martínez Usero, José Angel
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The decline of Spain (1500–1850): conjectural estimates [PDF]
, 2007 This article attempts to quantify the decline of Spain over the period 1500–1850. In contrast to earlier estimates that focus almost exclusively on Castilian agriculture, we look at trends in urbanisation and construct new measures of agricultural and ...
Prados de la Escosura, Leandro +1 more
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Descriptions of two new species of the family Scythrididae from Europe (Lepidoptera: Scythrididae)
SHILAP, 2019 Two new species of the family Scythrididae are described from Europe: Scythris spiniferella Nupponen & Savenkov, sp. n. from Southern Spain, and Scythris rowecki Nupponen & Savenkov, sp. n. from the Southern Ural Mountains, Russia.
K. Nupponen, N. Savenkov
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