Results 101 to 110 of about 5,198,158 (308)

Design, assembly, alignment and application of a versatile, open-source, single-pixel microscope

open access: yesScientific Reports
Single-pixel microscopy (SPM) is an emerging imaging technique in which a sample is illuminated with a series of micro-structured light patterns, typically generated by a digital micromirror device (DMD).
Samuel I. Zapata-Valencia   +5 more
doaj   +1 more source

A Fixed Effects Analysis of the Adoption of New Technologies in the Cuban Sugar Industry, 1899-1929 [PDF]

open access: yes, 1992
This paper focuses on the relationship between technical and institutional changes in Cuba a leader in the use of continuousprocess technologies being applied to cane sugar manufacture in the first three decades of the twentieth century. Using a fixed
Dye, Alan
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

No green growth without innovation. Bruegel Policy Brief 2009/07, November 2009 [PDF]

open access: yes, 2009
The 'green growth' debate is taking place in an oversimplified setting, largely disregarding the innovation factor. Technologies to mitigate climate change are being treated as given, or as emerging spontaneously, ignoring the fact that the portfolio of ...
Aghion, Philippe   +2 more
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Effect of the Micro Wire-EDM Process Parameters on the Recast Layer in the Molybdenum Micromachining [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2017
The Micro wire electrical discharge machining (Micro wire-EDM) process is a modern machining process with various applications in manufacturing micro-parts. The recast layer remaining on the machined surfaces is an inevitable complication of this process.
Mohammad Tahmasebipour   +3 more
doaj  

Harmony and Technology Enhanced Learning [PDF]

open access: yes, 2016
New technologies offer rich opportunities to support education in harmony. In this chapter we consider theoretical perspectives and underlying principles behind technologies for learning and teaching harmony.
Holland, Simon
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy