Results 71 to 80 of about 5,178,954 (288)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The pedagogical challenges to collaborative technologies [PDF]

open access: yes, 2009
Collaborative technologies offer a range of new ways of supporting learning by enabling learners to share and exchange both ideas and their own digital products.
Laurillard, Diana
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Neoliberalising bioethics: Bias, enhancement and economistic ethics [PDF]

open access: yes, 2008
In bioethics there is an ongoing debate about the ethical case for human enhancement through new biomedical technologies. In this debate there are both supporters and opponents of human enhancement technologies such as genetic improvements of cognitive ...
Birch, Kean
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

New frequencies, new monitoring technology

open access: yesNursing Management (Springhouse), 2003
Regulatory changes in available frequencies for wireless patient monitoring require many hospitals to implement new monitoring systems. Choose the best features of current technology, while allowing for future advances in both on- and off-site patient monitoring.
openaire   +3 more sources

Industry Evolution: New Technologies and New Firms [PDF]

open access: yes
This paper investigates the effects of employee mobility on industry evolution and technology diffusion by testing a dynamic industry equilibrium model introduced in Franco and Filson (1999).
April Mitchell Franco, Darren Filson
core  

The search for innovators and early adopters of e-collaborative technologies within small and medium sized enterprises in the UK [PDF]

open access: yes, 2007
New product diffusion theory predicts that innovators and early adopters are critical to the success of new innovations. The rate at which enterprises adopt e-Science technologies must therefore rely upon reliable market intelligence so that the critical
Brown, D H   +3 more
core  

Knowledge politics and new converging technologies: a social epistemological perspective [PDF]

open access: yes, 2009
The “new converging technologies” refers to the prospect of advancing the human condition by the integrated study and application of nanotechnology, biotechnology, information technology and the cognitive sciences - or “NBIC”.
Adleman L.M.   +46 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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