Results 81 to 90 of about 5,198,158 (308)

Knowledge politics and new converging technologies: a social epistemological perspective [PDF]

open access: yes, 2009
The “new converging technologies” refers to the prospect of advancing the human condition by the integrated study and application of nanotechnology, biotechnology, information technology and the cognitive sciences - or “NBIC”.
Adleman L.M.   +46 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

NEW TECHNOLOGIES IN BIOFUEL PRODUCTION [PDF]

open access: yes
Resource /Energy Economics and Policy,
Bothast, Rodney J.
core   +1 more source

The pedagogical challenges to collaborative technologies [PDF]

open access: yes, 2009
Collaborative technologies offer a range of new ways of supporting learning by enabling learners to share and exchange both ideas and their own digital products.
Laurillard, Diana
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hub and shroud fillets influence on the radial compressor stage efficiency

open access: yesEPJ Web of Conferences, 2015
Article describes numerical simulations of an air flow in the radial compressor stage in the NUMECA CFD software. During the tasks evaluating the stepped and straight impeller seals and hub and shroud fillets influence on working characteristics and flow
Syka Tomáš   +2 more
doaj   +1 more source

New technologies [PDF]

open access: yesCurrent Opinion in Neurobiology, 2010
Erin, Schuman, Xiaowei, Zhuang
openaire   +2 more sources

Visual Literacy and New Technologies [PDF]

open access: yes, 2003
This body of research addresses the connection between arts, identity and new technology, and investigates the impact of images on adolescent identities, the relationship between online modes of communication and cyber-bullying, the increasing ...
Bamford, Anne
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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