Determinants and spatial distribution of early newborn care in Somalia: evidence from the 2020 Somalia health and demographic survey. [PDF]
Ali AO +6 more
europepmc +1 more source
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li +11 more
wiley +1 more source
Wealth-based equity in essential newborn care practices in Ethiopia: A cross-sectional study. [PDF]
Delele TG +12 more
europepmc +1 more source
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang +11 more
wiley +1 more source
Exploring Indonesian fathers' educational needs in newborn care: A qualitative study. [PDF]
Agustina AN, Pratiwi A, Mahardika P.
europepmc +1 more source
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang +14 more
wiley +1 more source
Facility newborn and stillbirth data use and enabling factors at different levels of the health system: findings of the IMPULSE study across 142 sites in the Central African Republic, Ethiopia, Tanzania, and Uganda. [PDF]
Abathun F +17 more
europepmc +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Where to invest in neonatal survival programs in Nepal? A modelling study using Lives Saved Tool through scaling key interventions. [PDF]
Khanal GN, Giri N, Jha D, Chaulagain DR.
europepmc +1 more source

