Results 201 to 210 of about 524,540 (290)

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Advances and Gaps in Global Newborn Screening for Sickle Cell Disease. [PDF]

Int J Neonatal Screen
Shook LM, Ware RE.
europepmc   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Neonatal Genetic Screening Results for Spinal Muscular Atrophy in Romania: Insights from a 3-Years Pilot Program. [PDF]

Int J Neonatal Screen
Leanca MC, Onose G, Nicolae G, Neagu E, Vasile D, Bercu E, Balanescu OM, Capitanescu A, Munteanu C, Popescu C, Mirea A.   +10 more
europepmc   +1 more source

Gel‐Amin for Improving Extracellular Recordings of Cardiomyocytes in a 3D Microphysiological System

Advanced Electronic Materials, EarlyView.
This work combines a conductive collagen‐based hydrogel with a laser‐cut and assembly technique to fabricate microphysiological systems that improve extracellular recordings of cardiomyocytes in 3D on microelectrode arrays. The inclusion of choline acrylate into GelMA imparts a higher electrical conductivity and improves the signal‐to‐noise ratio of on‐
Dominic Pizzarella, Katelyn Neuman, Nolan Burson, Abigail N. Koppes, Ryan A. Koppes   +4 more
wiley   +1 more source

Methods and mechanisms for measuring and monitoring outcomes from newborn bloodspot screening: a scoping review.

Health Technol Assess
Scandrett K, Dinnes J, Morrison B, Coombe A, Agarwal R, Asare IA, Mead P, De Souza A, Elliman D, Lombardo S, Marshall J, Taylor-Phillips S, Takwoingi Y.   +12 more
europepmc   +1 more source

Developing and validating a neonatal screening tool for congenital anomalies to be used in low- and middle-income country settings. [PDF]

BMJ Glob Health
Gebreselassie HA, Lakhoo K.
europepmc   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Ralstonia pickettii as an emerging pediatric pathogen: a mini-review of current evidence. [PDF]

Front Pediatr
Rodriguez-Saldaña CA, Chiroque-Zavala M, Quindes-Jaimes M, Muñoz-Vílchez GM, Alcántara-Sánchez KI, Montoya-Reátegui A, Quiroga-Taboada A, Farfán-Chávez LG, Reyes-Chávez D, Flores-Rodriguez JJ.   +9 more
europepmc   +1 more source

Characterizing the causes and consequences of calcium oxalate crystal presence in Vitis riparia

American Journal of Botany, EarlyView.
Abstract Premise Calcium oxalate biomineralization in plants is phylogenetically widespread and morphologically diverse, but the function of these inorganic crystals is an area of active debate. The variety of environmental conditions that produce the crystals, as well as the inconsistent evidence that they provide antiherbivore defense across plant ...
Carolyn D. K. Graham, Samantha Molino, Addison L. Yerks, Marjorie Weber   +3 more
wiley   +1 more source