Results 171 to 180 of about 212,548 (293)

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

open access: yesAdvanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao   +16 more
wiley   +1 more source

Newborn Screening for Congenital Heart Disease: A Five-Year Study in Shanghai. [PDF]

open access: yesInt J Neonatal Screen
Tian Y   +13 more
europepmc   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao   +20 more
wiley   +1 more source

Evaluation of the Florida Newborn Screening Program Education Campaign. [PDF]

open access: yesInt J Neonatal Screen
Richey M, Wilson CB, Jia M, Galbraith T.
europepmc   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

A Common Mutation Is Associated with a Mild, Potentially Asymptomatic Phenotype in Patients with Isovaleric Acidemia Diagnosed by Newborn Screening [PDF]

open access: bronze, 2004
Regina Ensenauer   +14 more
openalex   +1 more source

Expanded Newborn Screening in Italy: The First Report of Lombardy Region. [PDF]

open access: yesInt J Neonatal Screen
Berardo C   +23 more
europepmc   +1 more source

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