Results 101 to 110 of about 384,008 (281)

Peculiarities of health and bone metabolism of children born through IVF

open access: yesМедицинский совет, 2019
The multiple increase in the number of «conceived in vitro» newborns is accompanied by an increase in the number of questions arising around this method of infertility treatment Evaluating the potential health realities of this category of children, it ...
N. A. Druzhinina, D. R. Merzlyakova
doaj   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

On Charlie Gard: Ethics, Culture, and Religion [PDF]

open access: yes, 2018
The 2017 story of Charlie Gard is revisited. Upon the British High Court’s ruling in favor of the physicians that the infant should be allowed to die without the experimental treatment, the view of the public as well as the opinions of bioethicists and ...
Lee, Marvin J. H.
core  

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

open access: yesAdvanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks   +14 more
wiley   +1 more source

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]

open access: yes, 2018
Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco   +7 more
core   +1 more source

Advanced Design for Weakly Coupled Resonators by Automatic Active Optimization

open access: yesAdvanced Materials Technologies, EarlyView.
An Automatic Active Optimization (AAO) strategy integrates machine learning predictors and genetic algorithms in a closed‐loop workflow. By iteratively expanding its dataset with new discoveries, AAO overcomes the limits of conventional methods. This approach finds superior microstructural designs beyond the initial sample space. We demonstrate this on
Wei Yue   +8 more
wiley   +1 more source

HIP JOINT PATHOLOGY IN THE NEONATAL PERIOD

open access: yesTravmatologiâ i Ortopediâ Rossii, 2011
The frequency of developmental hip dysplasia among newborns and its change with ultrasound application are presented. The ultrasound estimation of coxofemoral joints in children of the first days of life is resulted and the analysis of conformity of the ...
A. G. Baindurashvili, I. Y. Chukhraeva
doaj   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

open access: yesAdvanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi   +12 more
wiley   +1 more source

Impact of aging on the evolution of cooperation in the spatial prisoner's dilemma game

open access: yes, 2009
Aging is always present, tailoring our interactions with others and postulating a finite lifespan during which we are able to exercise them. We consider the prisoner's dilemma game on a square lattice, and examine how quenched age distributions and ...
Attila Szolnoki   +8 more
core   +1 more source

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