Results 161 to 170 of about 9,226,576 (359)

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

open access: yesChronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi   +7 more
wiley   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

Prognostic impact of peak oxygen consumption in heart failure: A systematic review and meta‐analysis

open access: yesESC Heart Failure, EarlyView.
Based on 64 studies, each 1 mL/kg/min increase in VO2peak significantly reduced all‐cause mortality (HR: 0.86, 95% CI 0.82–0.90) and combined outcomes of ventricular assist device, transplant and all‐cause mortality (HR: 0.84, 95% CI 0.79–0.89) in patients with heart failure, though no significant association was observed with cardiovascular mortality (
Konstantinos Prokopidis   +6 more
wiley   +1 more source

Minimization or withdrawal of oral pharmacotherapy in chronic heart failure patients with improved myocardial function: A systematic review

open access: yesEuropean Journal of Heart Failure, EarlyView.
This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.
Yuxiang Luo   +8 more
wiley   +1 more source

Intravenous ferric carboxymaltose in heart failure with iron deficiency (FAIR‐HF2 DZHK05 trial): Sex‐specific outcomes

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Aims Intravenous iron has emerged as a guideline‐recommended therapy in patients with heart failure and iron deficiency, but the potential sex‐related differences in efficacy are unknown. We aimed to assess sex‐specific outcomes in the Intravenous Iron in Patients with Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality
Mahir Karakas   +49 more
wiley   +1 more source

Phytochemistry, pharmacological insights, and food science applications of natural bioactive compounds from Ocimum species with a focus on essential oils

open access: yesFood Frontiers, EarlyView.
The article examines the phytochemistry, pharmacology, and food science applications of essential oils and extracts from Ocimum species (basil). It covers diverse extraction methods like hydrodistillation and microwave‐assisted extraction while discussing pharmacological benefits.
Oberdan Oliveira Ferreira   +13 more
wiley   +1 more source

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville   +5 more
wiley   +1 more source

Sedentary behavior during pregnancy and risk of pre‐eclampsia and/or gestational hypertension: A systematic review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Despite improvements in perinatal care, pre‐eclampsia remains a major cause of maternal and neonatal morbidity and mortality. Gestational hypertension and blood pressure are important intermediate endpoints for pre‐eclampsia. Sedentary behavior has emerged as an independent risk factor for chronic disease, regardless of physical ...
Lulu X. Pei, Shelby Marozoff
wiley   +1 more source

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