Results 41 to 50 of about 244,400 (363)

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

ELISA indireto para detecção de IgG antivírus da doença de Newcastle em soro de codorna Indirect ELISA for the detection of IgG specific to Newcastle disease virus in quail serum

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
An indirect ELISA for the detection of japanese quail IgG specific to Newcastle disease virus (NDV) was developed. The secondary anti-quail IgG was produced in Balb/c mice, by inoculating Freund's complete adjuvant emulsified japanese quail-IgG extract ...
D.D. Oliveira, A.V. Folgueras-Flatschart, R.B. Flatschart, J.S. Resende, J.T. Abreu, N.R.S. Martins   +5 more
doaj   +1 more source

Pengaruh Dosis Vaksin Newcastle Disease Inaktif Pada Itik Betina Terhadap Jumlah Sel Darah Putih Dan Titer Antibodi [PDF]

, 2016
This study are determines to: 1) the effect of ND vaccine dose to the number of white blood cells produced in the female ducks; 2) the effect of ND vaccine doses to the amount of antibody titers produced in the female ducks.
Pratama, L. (Luthfi), Santosa, P. E. (Purnama), Siswanto, S. (Siswanto)   +2 more
core  

Relationship between antihypertensive medications and cognitive impairment: Part I. review of human studies and clinical trials [PDF]

, 2016
Purpose of review: There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHMs) and dementia risk ...
Anstey, KJ, Carlson, MC, Peters, J, Peters, R, Schuchman, M, Yasar, S   +5 more
core   +2 more sources

Development of a Sensitive Electrochemical Aptasensor for Non‐Small Cell Lung Cancer Extracellular Vesicle Detection

Advanced Materials Interfaces, EarlyView.
A novel electrochemical aptasensor enables the selective detection of lung cancer‐derived EVs by targeting the CD44 surface marker. The sensor uses a self‐assembled monolayer (SAM) for aptamer immobilization and achieves label‐free EV detection through electrochemical impedance spectroscopy.
Zarinah M. Amin, Volker Nock, Paula Brooksby, Renee V. Goreham   +3 more
wiley   +1 more source

Profil Titer Antibodi Newcastle Disease (Nd) Dan Avian Influenza (Ai) Pada Itik Petelur Fase Grower Di Kecamatan Gadingrejo Kabupaten Pringsewu [PDF]

, 2014
This study aimed to determine the antibody titre against Newcastle Disease (ND) and AvianInfluenza (AI) in laying duck of grower phase. This study has been conducted in December 2013--January 2014 in Gadingrejo Subdistrict, Pringsewu District, Lampung ...
Santosa, P. E. (Purnama), Siswanto, S. (Siswanto), Yusmariza, N. (Novia)   +2 more
core  

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

The Efficacy of Inactivated Oil Emulsion Newcastle Disease Vaccine [PDF]

, 1983
The preparation of an experimenta1 oi1 emulsion Newcastle disease vaccine is described and its efficacy was evaluated in broiler chickens. A plaque purified clone of Mukteswar strain of Newcastle disease virus designated UPM-AC/2 was used for the ...
Rahaju, Ernawati
core  

Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]

, 2011
Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Antonis, A.F.G., Harmsen, M.M., Kortekaas, J.A., Moormann, R.J.M.   +3 more
core   +2 more sources

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

Advanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle, Eleanor Swanson, Luka Jovanovic, Suraya Yusuf, Lucy Thompson, Hugo Layard Horsfall, William Muirhead, Luke Bashford, Jamie Brannigan   +8 more
wiley   +1 more source