Results 41 to 50 of about 130,821 (262)

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Newcastle disease virus pathotypes [PDF]

Avian Pathology, 1974
The clinical signs, mortality and postmortem findings following infection of six-week-old chicks with nine strains of Newcastle disease virus were studied. Although strains could be divided into four pathotypes the divisions were not clear-cut. The most prominent feature of disease following infection by two isolates from the post-1970 USA epidemic, a ...
D J, Alexander, W H, Allan
openaire   +2 more sources

Reduced‐Port Versus Multi‐Port Laparoscopic Colectomy for Colorectal Cancer: A Systematic Review, Meta‐Analysis, and Meta‐Regression

Annals of Gastroenterological Surgery, EarlyView.
Reduced‐port laparoscopic colectomy (RPLC) for colorectal cancer offers modest intraoperative benefits, including shorter operative time and lower blood loss, while maintaining comparable postoperative recovery, lymph node yield, and complication rates to multi‐port laparoscopic colectomy (MPLC).
Ayesha Shaukat, Saad Ashraf, Hamza Irfan, Muhammad Shahmeer Ullah Shah, Yumna Khabir, Santosh Sah, Um E. Abiha Batool, Muhammad Zain Ul Haq, Omer Bin Khalid Jamil, Aymar Akilimali   +9 more
wiley   +1 more source

STUDI HISTOPATOLOGI PADA LIMPA DAN BURSA FABRICIOUS AYAM NEWCASTLE DISEASE DARI KASUS LAPANG HISTOPATHOLOGY (STUDIES ON SPLEEN AND BURSA OF FABRICIUS OF NEWCASTLE DISEASE CHICKHENS FROM FIELD CASE)

Jurnal Veteriner, 2018
Newcastle Disease merupakan penyakit unggas yang sangat menular dan sangat mematikan pada semua unggas. Penelitian ini bertujuan mengetahui lesi dan distribusi virus Newcastle disease pada organ limpa dan bursa Fabricious ayam dari kasus-kasus lapangan ...
Etriwati Etriwati, Ekowati Handharyani, Surachmi Setiyaningsih   +2 more
doaj   +1 more source

Effects of Newcastle disease vaccine on the liver and antioxidant enzymes of chicks [PDF]

Iraqi Journal of Veterinary Sciences, 2019
Newcastle disease is a highly contagious disease of domestic and wild birds result in huge economic losses due to extreme morbidity and mortality. The aim of this paper is to explore the possibility of the harmful impact of Newcastle disease vaccine on ...
N. Mustafa
doaj   +1 more source

Improving outcomes for transplantation in failing Fontan—what is the next target?Central MessagePerspective

JTCVS Open, 2021
Objective: To identify the key contributors to postoperative mortality in patients undergoing orthotopic heart transplantation (OHT) for late Fontan failure.
Barbara Cardoso, MD, Andras Kelecsenyi, MD, Jonathan Smith, MB ChB, MRCP (UK), FRCA, Katrijn Jansen, MD, Fabrizio De Rita, MD, Mohamed Samy Nassar, MD, FRCS, Louise Coats, MBBS, PhD   +6 more
doaj   +1 more source

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang, Yuan Fang, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula R. Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, Laura Hagerty, Yetrib Hathout, Michael Ziemba, Lauren Morgenroth, Surajit Bhattacharya, Kanneboyina Nagaraju, Jyoti K. Jaiswal, Eric P. Hoffman   +16 more
wiley   +1 more source

Serological monitoring of Newcastle disease in the Russian Federation in 2023–2024

Ветеринария сегодня
Introduction. Newcastle disease is a highly contagious viral infection of birds that is reported in many countries around the world. Newcastle disease cases shall be notified to the World Organization for Animal Health.Objective.
Marina A. Volkova, Irina A. Chvala, Polina S. Yaroslavtseva, Maria A. Kulagina, Olga S. Osipova, Nelli A. Guseva, Dmitry B. Andreychuk   +6 more
doaj   +1 more source

The use of different types of Montanide adjuvant in preparation of inactivated rabbit haemorrhagic disease virus (RHDV) vaccine [PDF]

Veterinary Medical Journal - Giza, 2017
Background: Rabbit viral haemorrhagic disease (RVHD) is characterized by high mortality in adult rabbits causing severe economic losses. Vaccination against RHDV is the main preventive method.
Salman A, Samah Abodalal
doaj   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source