Results 31 to 40 of about 32,471 (163)

Evolutionary dynamics of Newcastle disease virus

Virology, 2009
A comprehensive dataset of NDV genome sequences was evaluated using bioinformatics to characterize the evolutionary forces affecting NDV genomes. Despite evidence of recombination in most genes, only one event in the fusion gene of genotype V viruses produced evolutionarily viable progenies.
Miller, Patti J., Kim, L. Mia, Ip, Hon S., Afonso, Claudio L.   +3 more
openaire   +2 more sources

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Cell Fusion by Newcastle Disease Virus

Journal of General Virology, 1972
Strains of Newcastle disease virus (NDV) induce cell fusion by two different mechanisms. The first, called ‘fusion from without’ (Bratt & Gallaher, 1969), is independent of virus multiplication, can be induced equally well by infective and non-infective virus and does not require host-specific or virus-specific macromolecular synthesis.
G, Poste, A P, Waterson, G, Terry, D J, Alexander, P, Reeve   +4 more
openaire   +2 more sources

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Survey on Visualization of Information Diffusion over Networks

Computer Graphics Forum, EarlyView.
Abstract Information Diffusion (ID) describes how a value (e.g., a pathogen, a rumor, a packet) spreads through an underlying “medium” network of elements (e.g., a social or computer network). Understanding the information diffusion process is essential to predicting trends, controlling misinformation, and enhancing decision‐making as well as ...
T. Baumgartl, M. Sondag, V. Filipov, M. Tuscher, S. Rajendran, S. Miksch, D. Archambault, A. Arleo, T. von Landesberger   +8 more
wiley   +1 more source

Variations in the Risk of New‐Onset Diabetes Following COVID‐19 Infection Across Body Mass Index, Deprivation, Ethnicity and Geographic Regions: Population‐Based Cohort Study in 42 Million People in England

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Evidence suggests that COVID‐19 may be associated with an increased risk of diabetes. We aimed to examine this association by investigating the role of socioeconomic and metabolic factors on the risk of new‐onset type 2 (T2D) and type 1 (T1D) diabetes after COVID‐19 diagnosis. Materials and Methods We conducted a retrospective, population‐
Sharmin Shabnam, Cameron Razieh, John Nolan, Nazrul Islam, Genevieve Cezard, Yogini V. Chudasama, Clare L. Gillies, Amitava Banerjee, Angela Wood, Kamlesh Khunti, Francesco Zaccardi, on behalf of the CVD‐COVID‐UK/COVID‐IMPACT Consortium   +11 more
wiley   +1 more source

Adverse Oral Health in Older Adults With Head and Neck Cancer (And Oral Potentially Malignant Disorders): A Systematic Review

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review evaluated oral health, including oral health‐related quality of life (OHRQoL), in older adults with head and neck cancer (HANC) or oral potentially malignant disorders (OPMDs). The PICO/PECO focus question for this study was: ‘What is the incidence/prevalence of adverse oral health (O) among people aged 60 ...
Ciaran Moore, Niamh Walls, Shaima Abujaber, Amanda Willis, Finbarr Allen, Gerry McKenna   +5 more
wiley   +1 more source

Black Fugitivity in the Sporting Workplace: The Story of Eniola Aluko

Gender, Work &Organization, EarlyView.
ABSTRACT Being a Black fugitive involves constant movement: to find and cultivate spaces of safety and hope. In this paper, I curate a sporting archive about the UK Black women's elite football player Eniola Aluko to read her as a Black fugitive. I demonstrate how she traversed a racist and anti‐Black sporting workplace—where she was unfairly demonized
Aarti Ratna
wiley   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

Haemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source