Results 21 to 30 of about 6,518,230 (243)

Metagenomic characterization reveals virus coinfections associated with Newcastle disease virus among poultry in Kenya [PDF]

, 2023
Newcastle disease (ND) is an endemic viral disease affecting poultry and causing massive economic losses. This cross-sectional purposive study detected coinfections that are associated with the Newcastle disease virus among poultry from selected regions ...
Munir, M., Nene, Vishvanath M., Oyola, Samuel O., Ommeh, S.C., Panyako, P.M., Nair, V., Lichoti, J.K., Musina, J., Kuria, S.N.   +8 more
core   +5 more sources

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Spatial Distribution and Seroprevalence of Newcastle Disease in Kaduna State, Nigeria

Folia Veterinaria, 2021
Newcastle disease is one of the greatest constraints to the development of poultry production in Nigeria. In this study, the spatial distribution of Newcastle disease antibodies was determined using the Geographic Information System. A total of 400 serum
Adanu W. A., Umoh J. U., Kabir J., Kwaga J. K. P., Otolorin G. R., Olufemi O. O.   +5 more
doaj   +1 more source

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

Emerging Microbes and Infections, 2021
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
Nicola S. Lewis, Ashley C. Banyard, Elliot Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, Alex Byrne, Saduakassova Meruyert (Akberovna), Jacqueline King, Timm Harder, Christian Grund, Steve Essen, Scott M. Reid, Adam Brouwer, Nikolay G. Zinyakov, Azimkhan Tegzhanov, Victor Irza, Anne Pohlmann, Martin Beer, Ron A. M. Fouchier, Sultanov Akhmetzhan (Akievich), Ian H. Brown   +21 more
doaj   +1 more source

Seroprevalence Investigation of Newcastle Disease in Rural Poultries of the Northern Provinces (Golestan, Gilan, and Mazandaran) of Iran [PDF]

Archives of Razi Institute, 2019
Rural poultry farming is common in the Northern provinces. Similar to commercial poultry, rural poultry is susceptible to most infectious diseases. In addition, by increasing the density of poultry farming, the probability of disease incidences has been ...
A. Alemian, S. A. Pourbakhsh, A. Shoushtari, H. Keyvanfar   +3 more
doaj   +1 more source

Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate

Veterinary Research, 2019
The G1-H9N2 avian influenza virus (AIV) has caused significant economic losses in the commercial poultry industry due to reduced egg production and increased mortality.
Giang Thu Nguyen, Fabienne Rauw, Mieke Steensels, Fiona Ingrao, Francesco Bonfante, Irit Davidson, Bénédicte Lambrecht   +6 more
doaj   +1 more source

Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]

, 2011
Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Adriaan F.G. Antonis, Kortekaas, J.A., Moormann, R.J.M., Jeroen Kortekaas, Antonis, A.F.G., Michiel M. Harmsen, Harmsen, M.M., Rob J.M. Moormann   +7 more
core   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus [PDF]

, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H., G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +7 more
core   +1 more source

Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]

, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Peeters, B.P.H., Strategic Infection Biology, Dep Infectieziekten Immunologie, G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +9 more
core   +2 more sources

Structural and functional relationship between the receptor recognition and neuraminidase activities of the Newcastle disease virus hemagglutinin-neuraminidase protein: Receptor recognition is dependent on neuraminidase activity [PDF]

, 2001
The terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy to the influenza virus neuraminidase ...
Paul J. Mahon, Deng, R.T., Jennifer M. Sauvron, Langedijk, J.P., Anne M. Mirza, Gisela M. Field, Johannes P. Langedijk, Sauvron, J.M., Iorio, R.M., Field, G.M., Ruitang Deng, Mirza, A.M., Mahon, P.J., Ronald M. Iorio   +13 more
core   +1 more source