Results 231 to 240 of about 298,387 (354)

The Construction and Discussion of the Practical Curriculum System of Labor Education in Higher Vocational Colleges in the New Era [PDF]

Zhongbao Ma, Peilan Cong, Xue Jiang, Yongqian Feng   +3 more
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Bridging Art and Algorithm: The Evolution of Plastic Surgery Across Eras. [PDF]

Indian J Plast Surg
Sharma RK.
europepmc   +1 more source

Is antipsychotic medication stigmatizing for people with mental illness? [PDF]

, 2009
Jenkins, Janis H, Sajatovic, Martha
core  

Ethnicity and Sociolinguistic Variation in San Francisco [PDF]

, 2010
Hall-Lew, Lauren
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Survival and Cost Analysis of Surgical Mitral Valve Replacement With Different Prostheses: A Nationwide Cohort Study in Taiwan. [PDF]

Med Sci Monit
Chien YS, Chung CH, Li JY.
europepmc   +1 more source

Cultivation of Youth Patriotism in the New Era: Current Situation, Objectives and Practical Approaches

Shuhui Fang
openalex   +2 more sources

Transplant Outcomes in Multiple Myeloma Patients Younger Versus Older Than 60 Years of Age in the Era of Newer Targeted Agents

Biology of Blood and Marrow Transplantation, 2011
Naik, S., Shope, D., Albright, C., Graham, R., Levitan, D., Zamkoff, K., D'Agostino, R., Hurd, D.   +7 more
openaire   +1 more source