Results 131 to 140 of about 1,643,238 (264)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Book Review: Geschichtstheater. Formen der "Living History" by Wolfgang Hochbruck

EXARC Journal, 2016
The dramatisation of history is ubiquitous in our postmodern everyday life: historical novels (as well as their TV adaptations, netting huge audience figures), documentaries, and stylistic references and citations evoking the past in fashion and ...
Ibrahim Karabed
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Newest Gadgets

, 1957
Photograph used for a story in the Oklahoma Times newspaper. Caption: "NEWEST GADGETS for safety and comfort which arrived in 11 new buses put into service Monday by City Bus Co., are being explained and tried out here.
Albright, Bob
core  

“Event review: I Experiment so I Participate” Italian Experimental Archaeology Festival: Experience in Didactics and Scientific Dissemination

EXARC Journal, 2019
Participation in archaeology is the basic “inclusive process” of a human community, which allows it to identify its cultural values. Experimental archaeology with its rediscovery of gestures and techniques allows re-appropriation, a sense of belonging ...
Massimo Massussi, Sonia Tucci, A. Sciancalepore, R. Laurito   +3 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Is Basket-ball a Danger? Part Two

, 1894
Part two of a two part discussion article that appeared in Young Men’s Era, the YMCA newspaper, examining the effect of basketball on the YMCA. The article contains the opinions of several YMCA Physical Directors throughout the United States.
Young Men's Era
core  

The Amber of This Moment: A Parable of Training Traditions. [PDF]

Ann Child Neurol Soc
Roach ES.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Navigating the intelligence revolution: transforming cardiovascular care through AI-driven innovation. [PDF]

Open Heart
Tang Y, Zhao K, Zhao S.
europepmc   +1 more source