Results 101 to 110 of about 157,079 (340)

The effect of heart failure nurse consultations on heart failure patients' illness beliefs, mood and quality of life over a six-month period [PDF]

, 2014
Aims and Objectives: To explore the effect contact with a heart failure nurse can have on patients' illness beliefs, mood and quality of life. Background: There is growing interest in patients' illness beliefs and the part they play in a patients ...
Bergeson, Blue, Broadbent, Brodie, Calvert, Cleland, Department of Health, Department of Health, Department of Health, Dudas, Ekman, Foxwell, Francis, Goodman, Hallas, Hirani, Hoekstra, Hunt, Jaarsma, Jiang, Juenger, Kitson, Kralik, Lainscak, Macinnes, McMurray, McWilliam, Mead, Mehta, Moss-Morris, Mulligan, National Institute for Health and Clinical Excellence, Rector, Rector, Remme, Riegel, Riegel, Riley, Royal College of Nursing, Sanders, Stewart, Weinman, World Health Organisation, Zigmond   +43 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Effectiveness of enhanced diabetes care to patients of South Asian ethnicity : the United Kingdom Asian Diabetes Study (UKADS) : a cluster randomised controlled trial [PDF]

, 2008
Background: Delivering high quality and evidence based healthcare to deprived sectors of the community is a major goal for society. We investigated the effectiveness of a culturally sensitive enhanced care package in UK general practice in improving ...
A Gumber, A Szczepura, AH Barnett, Anderson, Barnett, Brown, Campbell, Chaturvedi, Chobanian, Collins, Davies, Dolan, Gammon, Greenhalgh, Grundy, Gueyffier, Hansson, Hunt, Hussain-Gambles, JP O'Hare, Khunti, Mather, Millet, NT Raymond, O'Hare, Raftery, S Bellary, S Kumar, S Mughal, Saxena, Shekelle, Singer, Smeeth, Stone, Sullivan, Underwood, Williams, Wright   +37 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Maternity care and 'Every Child Matters' [PDF]

, 2009
The first part of the chapter will provide an introduction to maternity services in the UK and why it is the foundation of ‘Every Child Matters’. It is the earliest healthcare intervention of all for the child and it is essential to get it right for ...
Hutchinson, Fiona
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669) [PDF]

, 2014
Background Musculoskeletal pain is a major contributor to short and long term work absence. Patients seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with work issues.
A Kim Burton, A Mowlam, A Strauss, Annette Bishop, B McGuirk, C Black, Cabinet Office, Chris Main, CM Stapelfeldt, Danielle van der Windt, Department for Business Enterprise and Regulatory Reform, Department of Health, Department of Health, Health and Safety Executive, Department for Work and Pensions, Elaine M Hay, G Adams, G Waddell, G Waddell, G Waddell, G Waddell, G Waddell, G Waddell, G Waddell, Gail Sowden, Gwenllian Wynne-Jones, Health and Safety Executive, Health and Safety Executive, J Hiscock, JC Hill, K Kroenke, K Nice, K Nice, L Curtis, M Hann, M Lewis, M Van Tulder, MA Hanson, Martyn Lewis, Nadine E Foster, NAS Kendall, National Institute for Health and Clinical Excellence, Office for National Statistics, Office for National Statistics, PJ Watson, R Buchbinder, RJ Hayes, RL Franche, Sarah A Lawton, SM Eldridge, Sue Jowett, Tom Sanders, W Weidenhammer, WS Shaw   +51 more
core   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Evaluating the Effect of TeamSTEPPS on Teamwork Perceptions and Patient Safety Culture among Newly Graduated Nurses

BMC Nursing
Background Quality healthcare delivery is contingent upon effective teamwork and a patient safety-focused culture. TeamSTEPPS offers an evidence-based framework that enhances these competencies. However, the impact of TeamSTEPPS on newly graduated nurses,
Asmaa Elwan Hassan, Faten Ahmed Mohammed, Abeer Mohamed Zakaria, Ibrahim Abdullatif Ibrahim   +3 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1969
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1038/thumbnail ...

core   +1 more source