Results 211 to 220 of about 154,220 (300)

THE EFFECTIVENESS OF THE ORIENTATION PROGRAMME ON NEWLY RECRUITED BASIC BSC STAFF NURSES AT KRISHNA HOSPITAL, KARAD

Journal of Evolution of Medical and Dental Sciences, 2016
Rohini Babar, Kavita Kapurkar S, Sandhya Jagadale, Jadhav K S, Jagtap M P, Talbar S J   +5 more
openaire   +1 more source

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Meta-integration of qualitative studies on job stress experience of newly recruited nurses in intensive care unit

Zhiye weisheng yu yingji jiuyuan
XIA Tianjiao
doaj   +1 more source

Exploring nurse staffing and policy implications in times of crisis: the case of North Lebanon. [PDF]

BMC Nurs
Dankar MJ, Yazbik-Dumit N, Ammar W.
europepmc   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Newly qualified nurses' experiences of transition to professional practice in the context of COVID-19: a qualitative study. [PDF]

J Res Nurs
Jenkins C, Carter V, Smythe A.
europepmc   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Determinants of Hepatitis-Related Service Quality by Patients in Ghana: Implications for Quality Improvement. [PDF]

J Patient Exp
Ackon ED, Adjei CA, Kyei JM, Menkah W, Marfo EA, Asirifi MA.   +5 more
europepmc   +1 more source

Resisting medications: Moral discourses and performances in illness narratives [PDF]

, 2012
Cross, Jane, Murdoch, Jamie, Poland, Fiona, Salter, Charlotte, Smith, Jane   +4 more
core   +1 more source

KMT2C Loss Promotes NF2‐Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling

Advanced Science, EarlyView.
In NF2–wild‐type meningiomas, loss of the epigenetic regulator KMT2C suppresses NF2 transcription and inactivates Hippo signaling, driving tumor progression and increasing ferroptosis sensitivity. Restoration of histone acetylation reverses these effects and inhibits tumor growth, identifying KMT2C as a key regulator linking epigenetic control, NF2 ...
Liuchao Zhang, Yangfan Ye, Wei Gu, Xinyue Wang, Nuo Chen, Qixin He, Lei Xu, Pengzhan Zhao, Guoqiang Fu, Guangyao Yuan, Wenqian Shi, Honglu Chao, Yiming Tu, Jing Ji   +13 more
wiley   +1 more source