Results 81 to 90 of about 3,855,227 (269)
Texas Education Agency Annual Report
, 2020 The report describe the Texas Education Agency strategic plan, recruit, support and retain teachers and principals, build a foundation of reading and math, connect high school to career and college, improve low-performing schools, enrollment and ...
Texas Education Agency
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Old Lincoln Courthouse Postcard
, 2009 Color halftone glossy finish postcard. "Old Lincoln County Court House State Monument, Lincoln, New Mexico." Published by Schaaf's News Agency, Alamogordo, New ...
Gene Aiken
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Serbia city graphic 1:15,000 : Kragujevac / prepared ... by Defense Mapping Agency
, 1995 Ed. 3-DMA.Relief shown by contours and spot heights. "Map information as of 1993." "WGS 84." "Grid--1,000 meter UTM zone 34." "Printed by DMA 7-95." "This sheet falls within NK 34-02 and NL 34-11, 1501A 1:250,000 and 3183 II and 3182 I, M709, 1:50,000 ...
United States. Defense Mapping Agency
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BalisagesThe issue of “fake news” is as old as the press. The false news regarding the fall of Sevastopol in 1854 was cited by all newspapers and quickly went viral. Its success was due to both a technical innovation – the telegraph – and the control of the press
Lisa Bolz
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 2014 Link to the Food Standards Agency website. The Food Standards Agency is reponsible for food safety and food hygiene across the UK. Its website contains a number of guides and resource on food safety and food hygiene that are available under Crown ...
Food Standards Agency
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