Results 91 to 100 of about 3,855,227 (269)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2009 Glossy color halftone. Rocket launching tower at Roswell Museum - built in the early 1930's by Dr. Robert H. Goddard.
Gene Aiken
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Ghana needs local solution to the climate change menance-Nsenkyire
, 2011 The National Climate Change Committee for Ghana outlines recommendations for climate change adaptation in order to increase food security. “Food utilization, access, and availability” are impacted by extreme weather conditions and changes to rainfall ...
Ghana News Agency
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ACROSSThe study had as its general research objective the identification of ways to reflect Moldovan reality and project the image of the President of the Republic of Moldova, Maia Sandu, in Western and Eastern media. In order to achieve this goal, two news
Georgeta STEPANOV
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Agency submission to the Nutrition Advisory Group
, 1993 The Agency was established by the Government in September 1986 under the Combat Poverty Agency Act Under this Act the Agency has a statutory duty to advise and make recommendations to the Government on all aspects of economic and social planning in ...
Combat Poverty Agency (CPA)
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Tomsk Online News Journalism from the Perspective of Media Professionals
Вестник Новосибирского государственного университета. Серия: история, филологияThe article addresses how representatives of the Tomsk media community evaluate the development of Tomsk online news journalism, reflecting on their professional biographies and routine practices.
V. E. Lobyntseva
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source