Results 101 to 110 of about 3,855,227 (269)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Detecting Textual Reuse in News Stories, At Scale
International Journal of Communication, 2019 Motivated by the debate around “churnalism” and online media, this article develops, evaluates, and validates a computational method for detecting shared text between different news articles, at scale, using n-gram shingling.
Tom Nicholls
doaj
New Media and User Generated Content: An enthnographic analysis of citizen journalism taking Dokuz8haber news site as an example / Yeni Medya ve Kullanıcı Türevli İçerik: Dokuz8haber Sitesi Örneğinde Yurttaş Gazeteciliği Üzerine Etnografik Bir İnceleme [PDF]
Folklor/Edebiyat, 2015 This paper offers an analysis of a case study of digital platforms which involve user generated content in Turkey. A digital news agency, Dokuz8haber, which was formed by coming together of various citizen journalism initiatives via the use of new ...
Eylem Yanardağoğlu
doaj
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Texas Education Agency Annual Report
, 2019 The report describe the Texas Education Agency strategic plan, recruit, support and retain teachers and principals, build a foundation of reading and math, connect high school to career and college, improve low-performing schools, enrollment and ...
Texas Education Agency
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
The Role of Communal Ratings as Cues in Participation in Political User-generated News Websites
Palabra Clave, 2013 DOI: 10.5294/pacla.2013.16.3.2 Citizen journalists can participate in political user-generated news websites in different ways, including providing content, discussing with other users, and rating the content posted on the site.
Alcides Velásquez, Cliff Lampe
doaj
Impact of Patronage in News Agencies on Translating Political Discourse from Arabic into English
مجلة ابحاث كلية التربية الاساسيةPatronage is one of key elements that affecting translator and translation simultaneously. It presents powers (people, institutions) that can help or hinder reading, writing, and rewriting of literature.
Rusul Loay Saeed Al-Fahady +1 more
doaj +1 more source