Results 91 to 100 of about 71,839 (318)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Nursing Students and Conveying Bad News to Patients

open access: yesنشریه پرستاری ایران, 2018
Background & Aims: Communication skills are the foundation of clinical capabilities in healthcare providers. The process of delivering bad news is one of the most challenging aspects of clinical communication in health care, which has subtle ...
S Gholami Baroughi   +3 more
doaj  

වඩාත් යෝග්‍ය යෙදුම වන්නේ දූෂණයද? ලිංගික අපරාධයද?

open access: yes, 2020
This entry includes 3 write-ups and 3 infographics (all in Sinhala)In December 2020, Divaina, Mawbima and Lankadeepa used derogatory terms such as 'dooshanaya', 'kelaseema' in reporting news related to sexual assault and harassment that did not comply ...
Ethics Eye
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

2017 වසරේදී පුවත්පත් තුළ මාධ්‍ය ආචාර ධර්ම කඩවූ ආකාරය කෙබඳුද?

open access: yes, 2018
This entry includes an infographic and a write-up (both in Sinhala)This infographic describes media ethics violations i.e. revealing identity and personal details of minors and suspects, publishing without sources and not revealing the identity of the ...
Ethics Eye
core  

Transableism, Disability and Paternalism in Public Health Ethics: Taxonomies, identity Disorders and Persistent Unexplained Physical Symptoms [PDF]

open access: yes, 2006
Transableism is a term which refers to moving between states of being able and disabled by choice rather than by happenstance. Insofar as this may imply a choice to become dependent, claims upon the healthcare system are likely to result.
Mackenzie, Robin, Cox, Stephen
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

ආර්ථික අර්බුදය පිළිබඳ මාධ්‍ය වාර්තාකරණය 

open access: yes, 2022
This entry includes 4 write-ups and 4 infographics (both in Sinhala)In the month of June 2022, the following media ethics violations took place in relation to reporting of the Economic Crisis.
Ethics Eye
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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