Results 111 to 120 of about 71,839 (318)

හැඟීම් කළඹවන සුළු සිරස්තල, නිශේධනාත්මක නාමකරණ සහ මාධ්‍ය ආචාර ධර්ම

, 2023
This entry has one write-up and one infographic (both in Sinhala).On 7 July 2023, Sinhala newspaper Aruna published three news reports i.e. arrest of 58 people including 39 women in Jaffna after conflict between some groups, arrest of three young women ...
Ethics Eye
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

දිවි අහිමි කරගැනීම් සම්බන්ධව පාඨකයන් නොමඟ යවන ආකාරයේ වාර්තාකරණයන්

, 2020
This entry includes 13 write-ups and 15 infographics (All in Sinhala)In the month of September 2020, Mawbima, Divaina, Daily Mirror, Aruna, Lankadeepa violated media ethics in reporting suicide by not mentioning helplines, simplifying the reason for ...
Ethics Eye
core  

Ethics and social networking sites: A disclosive analysis of Facebook

, 2010
Paper has been accepted for publication in Information, Technology and People.Purpose: This paper provides insights into the moral values embodied by a popular social networking site (SNS), Facebook.
Light, B, McGrath, K, Light, BA, Ben Light, Kathy McGrath, Light, Ben, McGrath, Kathy   +6 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

දිවි අහිමිකරගනීම් පිළිබඳ පුවත් වාර්තාකරණය: සිද්ධිය සරල කිරීම, සියදිවි නසා ගැනීමේ ක්‍රමය අනාවරණය කිරීම සහ උපකාරක අංක සඳහන් නොකිරීම

, 2020
This entry includes 5 write-ups and 5 infographics. (both in Sinhala)In the month of October 2020, Sinhala newspapers such as Divaina, Dinamina, Aruna, Mawbima, Lankadeepa reported news related to suicide.
Ethics Eye
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Building Trust in AI-Human Partnerships: Exploring Preferences and Influences in the Manufacturing Industry

Management Systems in Production Engineering
The incorporation of artificial intelligence (AI) into industrial processes has seen substantial development, characterized by the shift from Industry 4.0 to the future concept of Industry 5.0.
Żywiołek Justyna
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source