Results 101 to 110 of about 895,293 (294)

Differences between Health Related News Articles from Reliable and Unreliable Media

, 2018
In this study, we examine a collection of health-related news articles published by reliable and unreliable media outlets. Our analysis shows that there are structural, topical, and semantic differences in the way reliable and unreliable media outlets conduct health journalism.
Dhoju, Sameer, Rony, Md Main Uddin, Hassan, Naeemul   +2 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Demographics of Mobile News Habits Men, College Grads and the Young are more Engaged [PDF]

, 2012
In the growing realm of mobile news, men and the more highly educated emerge as more engaged news consumers, according to this new study by the Pew Research Center's Project for Excellence in Journalism, in collaboration with The Economist Group.

core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Between Narratives and Climate Justice: Globo and UOL’s Coverage of Activism at the COPs [PDF]

Ambiente & Sociedade
Although climate change is increasingly covered in the media, the narratives surrounding socio-environmental issues have never been neutral or unified. This study examines how the largest Brazilian media conglomerates, Globo and UOL, covered the popular ...
Tainá Yumi Patriani, Ergon Cugler de Moraes Silva   +1 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The portrayal of food marketing policy by Canadian news media

Critical Public Health
Unhealthy food marketing influences children’s food preferences, intake and rates of obesity. Currently, there is no mandatory national food marketing policy that restricts food marketing to youth in Canada.
Grace Gillis, Julia Soares Guimarães, Monique Potvin Kent   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Motivierte Zweifel. Wie die Voreinstellungen der Rezipienten zum Berichterstattungsgegenstand ihre Wahrnehmung der Medienglaubwürdigkeit beeinflussen

Medien & Kommunikationswissenschaft, 2018
Right-wing populist groups’ accusations of a ‘lying’ press and the increasing fear of the effects of fake news on public opinion formation give rise to the question of how trust in the news media can be explained.
Marcus Maurer, Pablo Jost, Milan Pfoh, Maximiliane Porath, Lea Wilke   +4 more
doaj   +1 more source