Results 121 to 130 of about 71,990 (298)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

World News Tonight with Peter Jennings [PDF]

, 2002
World News Tonight with Peter Jennings.
ABC News
core  

NEWS＆TOPICS

JSTnews, 2023
  +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

U.S. News Outlets - Network of Shared Topics [PDF]

Journal of Social Structure, 2010
Katherine Ognyanova
doaj   +1 more source

Structural–Semantic Term Weighting for Interpretable Topic Modeling with Higher Coherence and Lower Token Overlap

Information
Topic modeling of large news streams is widely used to reconstruct economic and political narratives, which requires coherent topics with low lexical overlap while remaining interpretable to domain experts.
Dmitriy Rodionov, Evgenii Konnikov, Gleb Golikov, Polina Yakob   +3 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Extracting Causal Relations between News Topics from Distributed Sources [PDF]

, 2013
The overwhelming amount of online news presents a challenge called news information overload. To mitigate this challenge we propose a system to generate a causal network of news topics.
Miranda Ackerman, Eduardo Jacobo
core   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Discovering Ephemeral Associations among news topics [PDF]

, 2001
News reports are an important source of information about society. Their analysis allows to understand its current interests and to measure the social importance and influence of different events.
M. Montes-y-gómez, A. Gelbukh, A. López-lópez   +2 more
core