Results 61 to 70 of about 3,611,094 (240)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Misinformation in action: Fake news exposure is linked to lower trust in media, higher trust in government when your side is in power

open access: yesHarvard Kennedy School Misinformation Review, 2020
One major concern about fake news is that it could damage the public trust in democratic institutions. We examined this possibility using longitudinal survey data combined with records of online behavior.
Katherine Ognyanova   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Trust in Media, Trust in Science, Political Party, Big Five Personality Traits, and Vaccination Intention: A Cross‐Sectional Study

open access: yesHealth Science Reports
Background Trust in news media is important to examine in relation to COVID‐19 vaccination and personality has also been explored in regard to vaccination, where agreeableness, conscientiousness, and emotional stability have been shown to be connected to
Erika Katherine Johnson   +2 more
doaj   +1 more source

Investigating intergroup attitudes in Europe: Cross-national data on news media, attitudes towards newcomers, and socio-psychological indicators

open access: yesData in Brief, 2019
This dataset is part of a multidisciplinary project that investigates the relationship between attitudes of the adult population towards ‘newcomers’, and news media consumption and trust in Belgium, France, the Netherlands, and Sweden in 2017 (N = 6000).
David De Coninck   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

News Credibility on Facebook: The Role of Media and Intermediary Trust and Their Interplay

open access: yesInternational Journal of Communication
On social network sites, news media have lost their dominance as news sources, as individual actors (family members, friends) play the role of news intermediaries.
Lukáš Slavík   +2 more
doaj  

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