Results 81 to 90 of about 3,611,094 (240)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Who trusts the news media? Exploring the factors shaping trust in the news media in German-speaking Switzerland

open access: yesStudies in Communication Sciences, 2019
Although a decline of trust in the news media can be observed in many countries, in international comparison, Switzerland is still considered one of the countries with a relatively high level of media trust. Nevertheless, knowledge concerning the factors
Dorothee Arlt
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Construction Workers Health Trust activity report.

open access: yes, 2001
The Construction Workers Health Trust was founded following a decision taken at the Construction 2000 Conference in May 1994 by the Construction Group of Unions affiliated to the Irish Congress of Trade Unions, to establish a body dedicated solely to ...
Construction Workers Health Trust
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Selective and consistent news avoidance in Aotearoa New Zealand: motivations and demographic influences

open access: yesKōtuitui
This study explores selective and consistent news avoidance in Aotearoa New Zealand. Existing research suggests that selective news avoidance rates are high in Aotearoa New Zealand (Myllylahti M, Treadwell G. 2023.
Alex Beattie, John Kerr, Richard Arnold
doaj   +1 more source

TRULLO - local trust bootstrapping for ubiquitous devices [PDF]

open access: yes, 2007
Handheld devices have become sufficiently powerful that it is easy to create, disseminate, and access digital content (e.g., photos, videos) using them.
Licia Capra   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The influence of sensationalist features in television news stories on perceived news quality and perceived sensationalism of viewers in different age groups

open access: yesStudies in Communication Sciences, 2018
This study investigates whether the decreased trust in news media can be explained by the increase in sensationalism in news. To this end, an experiment was conducted in which viewers (N = 288) evaluated sensationalist versus non-sensationalist ...
Mariska Kleemans   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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