Results 131 to 140 of about 1,444,385 (351)

Community dynamics and metagenomic analyses reveal Bacteroidota's role in widespread enzymatic Fucus vesiculosus cell wall degradation

Scientific Reports
Enzymatic degradation of algae cell wall carbohydrates by microorganisms is under increasing investigation as marine organic matter gains more value as a sustainable resource.
Jascha F. H. Macdonald, Pablo Pérez-García, Yannik K.-H. Schneider, Patrick Blümke, Daniela Indenbirken, Jeanette H. Andersen, Ines Krohn, Wolfgang R. Streit   +7 more
doaj   +1 more source

Fluorescence In Situ Hybridization, Immunohistochemistry, and Next-Generation Sequencing for Detection of EML4-ALK Rearrangement in Lung Cancer [PDF]

, 2015
Marina Pekar‐Zlotin, Fred R. Hirsch, Lior Soussan‐Gutman, Maya Ilouze, Addie Dvir, Theresa A. Boyle, Murry W. Wynes, Vincent A. Miller, Doron Lipson, Gary A. Palmer, Siraj M. Ali, Dekel Shlomi, Ronen Brenner, Paul A. Bunn, Nir Peled   +14 more
openalex   +1 more source

Evolution of genome sequencing techniques [PDF]

, 2016
The quality and the speed for genome sequencing has advanced at the same time that technology boundaries are stretched. This advancement has been divided so far in three generations.
Goebel Vázquez, Cristina, Henao Mejía, Luisa Maria   +1 more
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Mobster: accurate detection of mobile element insertions in next generation sequencing data [PDF]

, 2014
Djie Tjwan Thung, Joep de Ligt, Lisenka E.L.M. Vissers, Marloes Steehouwer, Mark Kroon, Petra de Vries, P. Eline Slagboom, Kai Ye, Joris A. Veltman, Jayne Y. Hehir‐Kwa   +9 more
openalex   +1 more source

Btrim: A fast, lightweight adapter and quality trimming program for next-generation sequencing technologies

, 2014
Btrim is a fast and lightweight software to trim adapters and low quality regions in reads from ultra high-throughput next-generation sequencing machines. It also can reliably identify barcodes and assign the reads to the original samples.
Kong, Yong
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Bacteria and fungi in acute cholecystitis. A prospective study comparing next generation sequencing to culture [PDF]

, 2019
Ruben Dyrhovden, Kjell Kåre Øvrebø, Magnus Nordahl, Randi Nygaard, Elling Ulvestad, Øyvind Kommedal   +5 more
openalex   +1 more source

Development of a Next-Generation Sequencing (NGS) Gene Panel for Lysosomal Storage Diseases [PDF]

, 2017
Molecular genetic testing has not been used extensively as the primary diagnostic test for LSDs but this may change with the advent of rapid, reliable and affordable high-throughput DNA sequencing, the so called next generation sequencing.
Alves, Sandra, Coutinho, Maria Francisca, Encarnação, Marisa, Nogueira, Célia, Ribeiro, Diogo, Silva, Lisbeth   +5 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source