Results 121 to 130 of about 1,096,418 (305)

Standardized RNA extraction protocol for Entamoeba species: advancing molecular diagnostics and amebiasis control

Frontiers in Cellular and Infection Microbiology
Amebiasis, caused by Entamoeba histolytica, remains a major public health challenge in endemic regions and is often misdiagnosed due to its morphological similarity to the non-pathogenic species E. dispar. The limitations of light microscopy and the high
Gabriele Cox, Gabriele Cox, Marília Melo, Marília Melo, Audrien Andrade, Audrien Andrade, Beatriz Müller, Beatriz Müller, Alexandre dos Santos, Alexandre dos Santos, Aline dos Santos Moreira, Aline dos Santos Moreira, Natassia Silva de Araujo, Daniel Moreira, Daniel Moreira, Thiago Parente, Thiago Parente, Wim Degrave, Helena Toma, Mariana Waghabi   +19 more
doaj   +1 more source

Understanding the Promises and Hurdles of Metagenomic Next-Generation Sequencing as a Diagnostic Tool for Infectious Diseases

Clinical Infectious Diseases, 2017
Metagenomic next-generation sequencing (mNGS) has emerged as a promising single, universal pathogen detection method for infectious disease diagnostics.
P. Simner, Steve Miller, K. Carroll
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Non-maize hosts outperform maize in sustaining fall armyworm population during off-season irrigation in the tropics

Frontiers in Plant Science
The fall armyworm (FAW), Spodoptera frugiperda, has emerged as a major global threat to maize production due to its highly invasive nature, absence of diapause, and capacity for continuous reproduction in tropical environments. While off-season irrigated
Yohannes Ebabuye Andargie, Yohannes Ebabuye Andargie, Yohannes Ebabuye Andargie, Mintesnot Worku Bogale, Abaynew Jemal Jenber, Alemu Abate, Dong-Sun Lee, Jae-Ho Shin, Jae-Ho Shin   +8 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Community dynamics and metagenomic analyses reveal Bacteroidota's role in widespread enzymatic Fucus vesiculosus cell wall degradation

Scientific Reports
Enzymatic degradation of algae cell wall carbohydrates by microorganisms is under increasing investigation as marine organic matter gains more value as a sustainable resource.
Jascha F. H. Macdonald, Pablo Pérez-García, Yannik K.-H. Schneider, Patrick Blümke, Daniela Indenbirken, Jeanette H. Andersen, Ines Krohn, Wolfgang R. Streit   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source