From Somatic Variants Toward Precision Oncology: An Investigation of Reporting Practice for Next-Generation Sequencing-Based Circulating Tumor DNA Analysis [PDF]
, 2019 Rongxue Peng +8 more
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Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Editorial: Immunopeptidomic Approaches for the Identification of Tumor (neo)Antigens
Frontiers in Immunology, 2022 Jennie R. Lill, Michal Bassani-Sternberg
doaj +1 more source
High-throughput pipeline for thede novoviral genome assembly and the identification of minority variants from Next-Generation Sequencing of residual diagnostic samples [PDF]
, 2015 T. Gallo Cassarino +11 more
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Supplementary Table 3 from Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas
, 2023 Oliver A. Zill +16 more
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Current Status of Next-Generation Sequencing-Based Cancer Genome Profiling Tests in Japan and Prospects for Liquid Biopsy [PDF]
, 2021 Yumi Yoshii +2 more
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The chemistry of next-generation sequencing
Nature Biotechnology, 2023 Raphaël Rodriguez, Yamuna Krishnan
semanticscholar +1 more source
The Technology and Innovation Unit of the National Institute of Health: A sequencing and bioinformatics core facility specializing in public health genomics [PDF]
, 2019 The National Institute of Health (INSA) has a long tradition in investigating the molecular etiology of genetic and complex diseases. These activities greatly benefit from centralized sequencing services provided by the Technology and Innovation Unit ...
Ataíde Sampaio, Daniel +8 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Optimizing Splicing Junction Detection in Next Generation Sequencing Data on a Virtual-GRID Infrastructure [PDF]
, 2012 The new protocol for sequencing the messenger RNA in a cell, named RNA-seq produce millions of short sequence fragments. Next Generation Sequencing technology allows more accurate analysis but increase needs in term of computational resources. This paper
Abate, Francesco +5 more
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