Results 191 to 200 of about 1,460,723 (393)

Genome Sequence of a Divergent Avian Metapneumovirus from a Monk Parakeet (Myiopsitta monachus). [PDF]

open access: yes, 2019
Here, we report the coding-complete genome sequence of an avian metapneumovirus from a monk parakeet (Myiopsitta monachus), identified by metagenomic next-generation sequencing during an investigation into a disease outbreak in a captive parrot breeding ...
Clubb, Susan   +2 more
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Opacity complexity of automatic sequences. The general case [PDF]

open access: yesarXiv
In this work we introduce a new notion called opacity complexity to measure the complexity of automatic sequences. We study basic properties of this notion, and exhibit an algorithm to compute it. As applications, we compute the opacity complexity of some well-known automatic sequences, including in particular constant sequences, purely periodic ...
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Genetic landscape and clinical outcomes of autosomal recessive polycystic kidney disease in Kuwait

open access: yesHeliyon
Background: Autosomal recessive polycystic kidney disease (ARPKD), a rare genetic disorder characterized by kidney cysts, shows complex clinical and genetic heterogeneity.
Mariam E. Alhaddad   +11 more
doaj  

Comparison of next generation sequencing technologies for transcriptome characterization [PDF]

open access: gold, 2009
P. Kerr Wall   +15 more
openalex   +1 more source

Efficient generation of odd order de Bruijn sequence with the same complement and reverse sequences [PDF]

open access: yesarXiv
Experimental results show that, when the order $n$ is odd, there are de Bruijn sequences such that the corresponding complement sequence and the reverse sequence are the same. In this paper, we propose one efficient method to generate such de Bruijn sequences. This solves an open problem asked by Fredricksen forty years ago for showing the existence of
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa

open access: yesVirus Research
Respiratory syncytial virus (RSV) is the most predominant viral pathogen worldwide in children with lower respiratory tract infections. The Coronavirus disease 2019 (COVID-19) pandemic and resulting nonpharmaceutical interventions perturbed the ...
Hlengiwe Sondlane   +8 more
doaj  

NGSView: an extensible open source editor for next-generation sequencing data [PDF]

open access: green, 2009
Erik Arner   +2 more
openalex   +1 more source

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