Results 101 to 110 of about 290,563 (288)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

NEXUS portal, Vol. 2, issue 4

, 2008
The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
Coen, Stephanie, University of British Columbia. NEXUS Research Unit   +1 more
core   +1 more source

Revisiting the macroeconomic variables and economic growth nexus: A Markov regime-switching approach

Economic Journal of Emerging Markets, 2022
Purpose ―Current paper assesses the impact of macroeconomic variables on Pakistan's economic growth. Method ― This study analyzed the data using the Markov Regime switching (MS) model using monthly data for 1981-2020.
Asma Fiaz, Nabila Khurshid, Ahsan ul Haq Satti   +2 more
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

NEXUS portal, Vol. 2, issue 1

, 2008
The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
University of British Columbia. NEXUS Research Unit
core  

Role of alumni associations in their alma mater: An exploratory study on higher education institutions of Kathmandu Valley

Social Sciences and Humanities Open
The role of alumni and alumni associations remains a largely untapped resource and an unexplored area of research in Nepal. This study researches the current status and contributions of alumni associations, particularly in the context of Kathmandu Valley,
Prakriti Thapa, Suraj Parajuli, Tulasi Acharya, Umed Pun   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

NEXUS portal, Vol. 1, issue 2

, 2007
The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
University of British Columbia. NEXUS Research Unit
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

NEXUS portal, Vol. 1, issue 3

, 2007
The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
University of British Columbia. NEXUS Research Unit
core