Results 111 to 120 of about 290,563 (288)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
NEXUS portal, Vol. 3, issue 1, Winter 2009
, 2009 The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
Coen, Stephanie +1 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2007 The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.Applied Science, Faculty ofNursing, School ...
University of British Columbia. NEXUS Research Unit
core
NEXUS portal, Vol. 3, issue 2, Spring 2009
, 2009 The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.
Coen, Stephanie +1 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
NEXUS portal, Vol. 3, issue 3, Summer 2009
, 2009 The NEXUS Portal provides an in-depth profile of the research and achievements of NEXUS on a quarterly basis.
Coen, Stephanie +1 more
core +1 more source
Développement Durable et TerritoiresEcological modernization, when it comes to the generation of electricity, supposes a transition towards renewable primary energy sources, like wind or sun, and transition processes are in general analyzed in terms of technical advances and gaps. They are
François-Michel Le Tourneau +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source