Results 121 to 130 of about 290,563 (288)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The role of peer review and science for advancing public understanding
Water-Energy Nexus, 2020 Hyunook Kim +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The teaching-research-industry-learning nexus in information and communications technology [PDF]
, 2012 The teaching-research nexus concept has been extensively examined in the higher education literature, and the importance of industry linkages in information and communications technology (ICT) education has also been widely discussed.
Koppi, T., McGill, T., Armarego, J.
core
NEXUS Seminar: Complementary Medicine Education and Outcomes
, 2009 The Complementary Medicine Education and Outcomes (CAMEO) program is a collaborative UBC/BC Cancer Agency research initiative that aims to develop and evaluate evidence-based decision support for people living with cancer and their significant others who
Truant, Tracy, Balneaves, Lynda
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Node and Regime: Interdisciplinary Analysis of Water-Energy-Food Nexus in the Mekong Region
Water Alternatives, 2015 Understanding complex phenomena such as the water-energy-food nexus (resource nexus) requires a more holistic, interdisciplinary inquiry. Spurred by a sense of imbalance in approaches to the nexus dominated by integrated assessment/complex systems ...
Tira Foran
doaj