Results 201 to 210 of about 396,196 (289)

Canonical NF-κB Pathway as a Central Regulator of Obesity-Associated Inflammation: A Narrative Review. [PDF]

Biomedicines
Petrascu FM, Matei SC, Olteanu GE, Barna R, Marian C.   +4 more
europepmc   +1 more source

Prussian blue nanoparticles prevent RANKL ‐induced osteoclastogenesis by scavenging ROS and inactivating NF ‐ κB / MAPK signaling pathways [PDF]

Jiancheng Yang, Qinghua Tang, S.B. Li, Lei Yang, Ming Yang, Q. Li, Yan Feng, Mingming Pan, Yuhong Zeng   +8 more
openalex   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

The Association and Significance of MDM2 and NF-κB Protein Expression in Multiple Myeloma. [PDF]

Medicina (Kaunas)
Stanić Damić M, Grubešić A, Perić Z, Jonjić N, Seili-Bekafigo I, Hauser G, Jajaš N, Valković T.   +7 more
europepmc   +1 more source

Synthesis of lantadene analogs with marked in vitro inhibition of lung adenocarcinoma and TNF-α induced nuclear factor-kappa B (NF-κB) activation

, 2014
Monika Monika, Ankesh Sharma, Sharad Kumar Suthar, Vaibhav Aggarwal, Hong Boon Lee, Manu Sharma   +5 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

YTHDC2 promotes sepsis-induced cardiomyopathy by activating apoptosis and NF-κB pathway. [PDF]

Virulence
Wang W, Zhang TN, Wang ZM, Yang N, Liu CF.   +4 more
europepmc   +1 more source

Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-κB oncogenesis

, 2010
Andrew S. Liss, Ravi Tiwari, Jarmila Králová, Henry R. Bose   +3 more
openalex   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis. [PDF]

Front Pharmacol
Duan J, Hu X, Li T, Wu G, Dou P, Ouyang Z.   +5 more
europepmc   +1 more source