Results 131 to 140 of about 12,632,659 (295)

Inflammatory gene mRNA expression in human peripheral blood and its association with colorectal cancer

Journal of Inflammation Research, 2018
Reem Abdullah Alamro,1 Mohammad Mustafa,2 Abdulrahman K Al-Asmari2 1Deparment of Gastroenterology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia; 2Research Centre, Prince Sultan Military Medical City, Riyadh, Saudi Arabia Objective: The ...
Alamro RA, Mustafa M, Al-Asmari AK
doaj  

NF-kappa B as a therapeutic target in autoimmune disease

, 2007
NF-kappa B transmits signals from the cell surface to the nucleus. Signaling through cell surface receptors to activate NF-kappa B and mitogen-activated protein kinases through adaptor molecules is of critical importance to survival and activation of all
O'Sullivan, Brendan J., Thomas, Ranjeny, Brendan O’Sullivan, Thompson, Angus, Angus Thompson, Ranjeny Thomas   +5 more
core   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

Ubiquitin D Promotes Progression of Oral Squamous Cell Carcinoma via NF-Kappa B Signaling. [PDF]

Mol Cells, 2021
Song A, Wang Y, Jiang F, Yan E, Zhou J, Ye J, Zhang H, Ding X, Li G, Wu Y, Zheng Y, Song X.   +11 more
europepmc   +1 more source

[Regulation of NF-kappa B activity].

Postepy higieny i medycyny doswiadczalnej, 2003
Nuclear factor kappa B (NF-kappa B) is common proinflammatory transcription factor involved in expression of c.a. 300 different genes. It is usually present in the cytosol as an inactive complex and upon activation translocates into the nucleus. The mechanisms of activation of NF-kappa B are complex and they involve several different signaling pathways
Jakub, Siednienko, Wojciech A, Gorczyca
openaire   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Erratum: Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum. [PDF]

Theranostics, 2022
Qin X, Yan M, Wang X, Xu Q, Wang X, Zhu X, Shi J, Li Z, Zhang J, Chen W.   +9 more
europepmc   +1 more source

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

Animal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu, Tingting Liu, Xiangshu Cheng, Jianshe Wei   +3 more
wiley   +1 more source

The Role and Therapeutic Potential of NF-kappa-B Pathway in Severe COVID-19 Patients. [PDF]

Inflammopharmacology, 2021
Hariharan A, Hakeem AR, Radhakrishnan S, Reddy MS, Rela M.   +4 more
europepmc   +1 more source

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source